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Abnormal lens morphology

MedGen UID:
892382
Concept ID:
C0549651
Anatomical Abnormality
Synonyms: Abnormality of the lens; disease of lens of camera-type eye; disease or disorder of lens of camera-type eye; disorder of lens of camera-type eye; Lens disease; lens disorder; Lens issue; lens of camera-type eye disease; lens of camera-type eye disease or disorder
 
HPO: HP:0000517
Monarch Initiative: MONDO:0001176

Definition

An abnormality of the lens. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal lens morphology

Conditions with this feature

Pseudoexfoliation glaucoma
MedGen UID:
60133
Concept ID:
C0206368
Disease or Syndrome
Exfoliation syndrome (XFS) is a common age-related disorder of the extracellular matrix that is frequently associated with severe chronic secondary open-angle glaucoma and cataract. XFS syndrome may affect up to 30% of people over 60 years of age worldwide and is biomicroscopically diagnosed by abnormal microfibrillar deposits on ocular structures that line the aqueous-bathed surfaces of the anterior segment (summary by Schlotzer-Schrehardt and Naumann, 2006).

Professional guidelines

PubMed

Yu X, Chen W, Xu W
J Cataract Refract Surg 2020 Dec;46(12):1674-1679. doi: 10.1097/j.jcrs.0000000000000334. PMID: 32694307
Periman LM, Perez VL, Saban DR, Lin MC, Neri P
J Ocul Pharmacol Ther 2020 Apr;36(3):137-146. Epub 2020 Mar 12 doi: 10.1089/jop.2019.0060. PMID: 32175799Free PMC Article
Lawless M, Coster DJ, Phillips AJ, Loane M
Aust N Z J Ophthalmol 1989 Feb;17(1):33-60. doi: 10.1111/j.1442-9071.1989.tb00487.x. PMID: 2527524

Recent clinical studies

Diagnosis

Wang J, Yan H, Du Z, Zhang J, Wang W, Guo C
BMC Ophthalmol 2020 Jul 16;20(1):290. doi: 10.1186/s12886-020-01539-1. PMID: 32677902Free PMC Article

Prognosis

Wang J, Yan H, Du Z, Zhang J, Wang W, Guo C
BMC Ophthalmol 2020 Jul 16;20(1):290. doi: 10.1186/s12886-020-01539-1. PMID: 32677902Free PMC Article

Clinical prediction guides

Wang J, Yan H, Du Z, Zhang J, Wang W, Guo C
BMC Ophthalmol 2020 Jul 16;20(1):290. doi: 10.1186/s12886-020-01539-1. PMID: 32677902Free PMC Article

Supplemental Content

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