Classic view of this page
Precise Tumor Molecular Profile Testing
Clinical Genetic Test
Help
offered by
Myriad Genetics, Inc.
View lab's test page
LinkOut
GTR Test Accession: Help GTR000603555.1
CAP
PHARMACOGENOMIC
Last updated in GTR: 2022-11-18
View version history
Last annual review date for the lab: 2023-12-27 LinkOut
At a Glance
Test purpose: Help
Drug Response; Therapeutic management
Conditions (14): Help
Vemurafenib response; Cetuximab response; Dabrafenib response; ...
Genes (6): Help
BRAF (7q34), BRCA1 (17q21.31), BRCA2 (13q13.1), EGFR (7p11.2), ERBB2 (17q12), ...
Methods (3): Help
Biochemical Genetics - Immunohistochemistry: Gene expression profiling; ...
Target population: Help
Not provided
Clinical validity: Help
Not provided
Clinical utility: Help
Guidance for selecting a drug therapy and/or dose
Ordering Information
Offered by: Help
Myriad Genetics, Inc.
View lab's website
View lab's test page
Test short name: Help
Precise Tumor
Specimen Source: Help
Who can order: Help
  • Physician Assistant
  • Health Care Provider
  • Licensed Physician
Contact Policy: Help
Laboratory can only accept contact from health care providers. Patients/families are encouraged to discuss genetic testing options with their health care provider.
How to Order: Help
Complete test requisition form (available at https://myriad.com/oncology/precise-tumor/) and submit along with at least one tumor block with a cross-sectional tumor area of 25mm containing at least 80 micro meter of tumor. If only tumor slides are available, preparation instructions can be found at https://myriad-library.s3.amazonaws.com/Precise/Precise_Pathology_Guide.pdf
Order URL
Test service: Help
Clinical Testing/Confirmation of Mutations Identified Previously
Test development: Help
Test developed by laboratory (no manufacturer test name)
Informed consent required: Help
Decline to answer
Pre-test genetic counseling required: Help
No
Post-test genetic counseling required: Help
No
Recommended fields not provided:
Test Order Code, Lab contact for this test, Test strategy
Conditions Help
Total conditions: 14
Condition/Phenotype Identifier
Test Targets
Genes Help
Total genes: 6
Gene Associated Condition Germline or Somatic Allele (Lab-provided) Variant in NCBI
Methodology
Total methods: 3
Method Category Help
Test method Help
Instrument *
Immunohistochemistry
Gene expression profiling
RNA analysis
Next-Generation (NGS)/Massively parallel sequencing (MPS)
Sequence analysis of the entire coding region
Next-Generation (NGS)/Massively parallel sequencing (MPS)
* Instrument: Not provided
Clinical Information
Test purpose: Help
Drug Response; Therapeutic management
Clinical utility: Help
Guidance for selecting a drug therapy and/or dose
View citations (1)
  • Conroy JM, Pabla S, Glenn ST, Seager RJ, Van Roey E, Gao S, Burgher B, Andreas J, Giamo V, Mallon M, Lee YH, DePietro P, Nesline M, Wang Y, Lenzo FL, Klein R, Zhang S. A scalable high-throughput targeted next-generation sequencing assay for comprehensive genomic profiling of solid tumors. PLoS One. 2021;16(12):e0260089. doi:10.1371/journal.pone.0260089. Epub 2021 Dec 02. PMID: 34855780.

Variant Interpretation:
Are family members with defined clinical status recruited to assess significance of VUS without charge? Help
No.

Will the lab re-contact the ordering physician if variant interpretation changes? Help
No.
Recommended fields not provided:
Clinical validity, Target population, What is the protocol for interpreting a variation as a VUS?, Is research allowed on the sample after clinical testing is complete?, Sample negative report, Sample positive report
Technical Information
Test Comments: Help
Previousy registered in GTR as GTR000597554
Availability: Help
Tests performed
Specimen preparation performed in-house
Interpretation performed at an outside lab
Wet lab work performed at an outside lab
Report generated in-house

Test performance comments
Specimen preparation and report generation are performed in house. Wet lab work is performed by Intermountain Precision Genomics, a service of Intermountain Healthcare. Interpretation is done in collaboration with Pieriandx.
Analytical Validity: Help
https://myriad-library.s3.amazonaws.com/Precise/Precise+Tumor+Detailed+Sales+Aid.pdf
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
Yes

Method used for proficiency testing: Help
Formal PT program

PT Provider: Help
College of American Pathologists, CAP
Recommended fields not provided:
Test Confirmation, Assay limitations, Description of internal test validation method, Citations for Analytical validity, Description of PT method, Major CAP category, CAP category, CAP test list
Regulatory Approval
FDA Review: Help
Not provided
NYS CLEP Approval: Help
Number:
Status: Pending
Additional Information
Practice guidelines:
Consumer resources:

IMPORTANT NOTE: NIH does not independently verify information submitted to GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.