|
| Status |
Public on Sep 14, 2013 |
| Title |
Gene expression analysis of RB1 knockdown in bone in response to radiation |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The role of RB1 in response to radiation was examined in human osteoblasts. We demonstrate that RB1 induced SASP genes, a response which was attenuated in RB1 knockdown osteoblasts.
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| |
|
| Overall design |
Subconfluent hOB shEV and shRB1 cells were irradiated at 4 Gy using a 137Cesium source at a dose rate of 1.7 min/Gy and cell pelllets collected 0, 2, 4, 8, 16 and 24 hrs after irradiation.
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| |
|
| Contributor(s) |
Kansara M, Thomas D |
| Citation(s) |
24231354 |
| Submission date |
Sep 03, 2013 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Maya Kansara |
| E-mail(s) |
maya.kansara@petermac.org
|
| Phone |
0396561618
|
| Organization name |
Peter MacCallum Cancer Centre
|
| Department |
Research
|
| Lab |
Sarcoma Genomics and Genetics
|
| Street address |
St Andrews Place
|
| City |
Melbourne |
| State/province |
Victoria |
| ZIP/Postal code |
3002 |
| Country |
Australia |
| |
|
| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (36)
|
|
| Relations |
| BioProject |
PRJNA217904 |
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