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    shank3.L SH3 and multiple ankyrin repeat domains 3 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 108711262, updated on 11-Apr-2024

    Summary

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    Official Symbol
    shank3.L
    Official Full Name
    SH3 and multiple ankyrin repeat domains 3 L homeolog
    Primary source
    Xenbase:XB-GENE-17332122
    Locus tag
    XELAEV_18017949mg
    See related
    EnsemblRapid:ENSXLAG00005034753
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    psap2; prosap2; spank-2
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    Genomic context

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    See shank3.L in Genome Data Viewer
    Location:
    chromosome: 3L
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (95252411..95434810)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (79988899..80122909)

    Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene RAB, member of RAS oncogene family like 2B L homeolog Neighboring gene NME/NM23 nucleoside diphosphate kinase 6 L homeolog Neighboring gene arylsulfatase A, gene 2 L homeolog Neighboring gene uncharacterized LOC121401529 Neighboring gene mitogen-activated protein kinase 8 interacting protein 2 L homeolog Neighboring gene uncharacterized LOC108711265 Neighboring gene choline kinase beta L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ionotropic glutamate receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables synaptic receptor adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    SH3 and multiple ankyrin repeat domains protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      95252411..95434810
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041586629.1 → XP_041442563.1  SH3 and multiple ankyrin repeat domains protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8J1MM76
      Conserved Domains (7) summary
      cd09506
      Location:1822 → 1887
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      cd11984
      Location:662 → 713
      SH3_Shank3; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 3
      COG0666
      Location:351 → 499
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00992
      Location:757 → 850
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:364 → 395
      ANK; ANK repeat [structural motif]
      cd17177
      Location:190 → 276
      FERM_F0_SHANK3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 3 (SHANK3)
      pfam12796
      Location:301 → 395
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_041586630.1 → XP_041442564.1  SH3 and multiple ankyrin repeat domains protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8J1MM76
      Related
      ENSXLAP00005103886.1, ENSXLAT00005105905.1
      Conserved Domains (7) summary
      cd09506
      Location:1822 → 1887
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      cd11984
      Location:662 → 713
      SH3_Shank3; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 3
      COG0666
      Location:351 → 499
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00992
      Location:757 → 850
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:364 → 395
      ANK; ANK repeat [structural motif]
      cd17177
      Location:190 → 276
      FERM_F0_SHANK3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 3 (SHANK3)
      pfam12796
      Location:301 → 395
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_041586631.1 → XP_041442565.1  SH3 and multiple ankyrin repeat domains protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A8J1MND7
      Conserved Domains (5) summary
      cd11984
      Location:662 → 713
      SH3_Shank3; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 3
      COG0666
      Location:351 → 499
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00992
      Location:757 → 850
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:364 → 395
      ANK; ANK repeat [structural motif]
      cd17177
      Location:190 → 276
      FERM_F0_SHANK3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 3 (SHANK3)

    4. XM_018252835.2 → XP_018108324.1  SH3 and multiple ankyrin repeat domains protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8J1MM76
      Conserved Domains (7) summary
      cd09506
      Location:1822 → 1887
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      cd11984
      Location:662 → 713
      SH3_Shank3; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 3
      COG0666
      Location:351 → 499
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00992
      Location:757 → 850
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:364 → 395
      ANK; ANK repeat [structural motif]
      cd17177
      Location:190 → 276
      FERM_F0_SHANK3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 3 (SHANK3)
      pfam12796
      Location:301 → 395
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein Strain
    Heading Accession and Version

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