NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE217213 Query DataSets for GSE217213
Status Public on May 09, 2024
Title Drosophila models of dementia uncover shared and specific targets of TDP-43 proteinopathy across ALS and FTD relevant circuits
Organism Drosophila melanogaster
Experiment type Expression profiling by high throughput sequencing
Summary We developed a fly model of TDP-43 driven dementia by over-expressing YFP tagged human TDP-43 in the mushroom body neurons of the fly brain
 
Overall design We used GFP immunoprecipitation to pull down TDP-43 complexes from fly heads, obtained RNA-seq from total input and immunoprecipitated fractions, and then compared expression to identify genes enriched in the TDP-43 fraction
 
Contributor(s) Alsop E, Godfrey RK, Bjork RT
Citation(s) 37864255
NIH grant(s)
Grant ID Grant title Affiliation Name
RF1 NS091299 Translation dysregulation in neurodegeneration ABOR, UNIVERSITY OF ARIZONA DANIELA C ZARNESCU
Submission date Nov 03, 2022
Last update date May 09, 2024
Contact name Daniela Zarnescu
E-mail(s) dcz102@psu.edu
Organization name Penn State College of Medicine
Department Cellular and Molecular Physiology
Street address 500 University Drive Crescent Building C4605
City Hershey
State/province PA
ZIP/Postal code 17033
Country USA
 
Platforms (1)
GPL25244 Illumina NovaSeq 6000 (Drosophila melanogaster)
Samples (27)
GSM6706614 TDP-43 G298S input [21101503_503_input_S8]
GSM6706615 TDP-43 G298S input [21101506_506_input_S16]
GSM6706616 TDP-43 G298S input [21102203_203_input_S15]
Relations
BioProject PRJNA897920

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE217213_genecounts.txt.gz 675.2 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record
| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap