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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Nov 24, 2004 |
| Title |
Skeletal Muscle Response |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
To improve our understanding of the genetic reprogramming during the early phase of skeletal adaptation in response to endurance training, we employed cDNA microarray analysis to examine changes in mRNA expression in mouse plantaris muscle after a single bout voluntary running. Control untrained mice were compared with with R3h, R12h, P3h, P6h, P12h, P24h and R4w mice. We conclude that a single bout of voluntary running is sufficient to induce active remodeling processes, including cell proliferation, by a coordinated regulation of the genome in response to signals elicited from increased neuromuscular activity.
Keywords = Mouse skeletal muscle
Keywords = plantaris
Keywords = voluntary running
Keywords: time-course
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| Web link |
http://www.signaling-gateway.org/
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| Contributor(s) |
Choi S, Liu X, Li P, Akimoto T, Lee S, Gumbs C, Zhang M, Yan Z |
| Citation(s) |
16081620 |
| Submission date |
Nov 23, 2004 |
| Last update date |
Mar 16, 2012 |
| Contact name |
Sangdun Choi |
| E-mail(s) |
schoi@caltech.edu
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| Phone |
626-395-8732
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| Fax |
626-796-7066
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| Organization name |
California Institute of Technology
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| Department |
Biology
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| Lab |
Simon Lab
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| Street address |
1200 E. California Blvd
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| City |
Pasadena |
| State/province |
CA |
| ZIP/Postal code |
91125 |
| Country |
USA |
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| Platforms (1) |
| GPL254 |
Caltech 16K Oligo Mouse Array |
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| Samples (7)
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| GSM35396 |
Control (untrained) vs R4w (after 4 weeks running). |
| GSM35397 |
Control (untrained) vs P24h (24 hours after 12 hours running). |
| GSM35398 |
Control (untrained) vs P12h (12 hours after 12 hours running). |
| GSM35399 |
Control (untrained) vs R12h (0 hour after 12 hours running). |
| GSM35400 |
Control (untrained) vs R3h (running for 3 hours and sacrifice immediately). |
| GSM35401 |
Control (untrained) vs P3h (3 hours after 12 hours running). |
| GSM35402 |
Control (untrained) vs P6h (6 hours after 12 hours running). |
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| Relations |
| BioProject |
PRJNA91815 |
| Supplementary data files not provided |
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