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    CMU_039230 DNA mismatch repair protein MutL, putative [ Cryptosporidium muris RN66 ]

    Gene ID: 6994671, updated on 17-May-2024

    Summary

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    Gene symbol
    CMU_039230
    Gene description
    DNA mismatch repair protein MutL, putative
    Primary source
    CryptoDB:CMU_039230
    Locus tag
    CMU_039230
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Cryptosporidium muris RN66 (strain: RN66)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia; Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium
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    Genomic context

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    See CMU_039230 in Genome Data Viewer
    Location:
    chromosome: Unknown
    Exon count:
    1

    NW_002196570.1Genomic Context describing neighboring genes Neighboring gene cytosol aminopeptidase protein, putative Neighboring gene uncharacterized protein Neighboring gene ubiquitin family protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_002196570.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP-dependent DNA damage sensor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables mismatched DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mismatch repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MutLalpha complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA mismatch repair protein MutL, putative
    XP_002139205.1
    • encoded by transcript CMU_039230A

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NW_002196570.1 Reference assembly

      Range
      439470..441905 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002139169.1 → XP_002139205.1  DNA mismatch repair protein MutL, putative [Cryptosporidium muris RN66]

      See identical proteins and their annotated locations for XP_002139205.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      B6A9G5
      Conserved Domains (4) summary
      TIGR00585
      Location:2 → 328
      mutl; DNA mismatch repair protein MutL
      pfam16413
      Location:542 → 811
      Mlh1_C; DNA mismatch repair protein Mlh1 C-terminus
      cl00075
      Location:27 → 137
      HATPase_c; Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins
      cl02783
      Location:211 → 342
      TopoII_MutL_Trans; MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of type II DNA topoisomerases (Topo II) and DNA mismatch repair (MutL/MLH1/PMS2) proteins. This transducer domain is homologous to the second ...
    Nucleotide Protein
    Heading Accession and Version

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