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    Zfp956 zinc finger protein 956 [ Mus musculus (house mouse) ]

    Gene ID: 101197, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Zfp956provided by MGI
    Official Full Name
    zinc finger protein 956provided by MGI
    Primary source
    MGI:MGI:2141515
    See related
    Ensembl:ENSMUSG00000045466 AllianceGenome:MGI:2141515
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in early conceptus; inner cell mass; and oocyte. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in testis adult (RPKM 28.3), thymus adult (RPKM 11.9) and 27 other tissues See more
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    Genomic context

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    See Zfp956 in Genome Data Viewer
    Location:
    6 B2.3; 6 22.94 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (47930324..47942234)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (47953390..47965300)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 282 Neighboring gene predicted gene, 52899 Neighboring gene Zinc finger protein 212 Neighboring gene zinc finger protein 783 Neighboring gene STARR-positive B cell enhancer ABC_E8099 Neighboring gene nuclear encoded tRNA cysteine 57 (anticodon GCA) Neighboring gene ribosomal protein S2 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
    2. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    3. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Potential readthrough

    Included gene: Zfp783

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC101197

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178898.4 → NP_849229.2  uncharacterized protein LOC101197

      See identical proteins and their annotated locations for NP_849229.2

      Status: VALIDATED

      Source sequence(s)
      AK045736, AK133549, BC096536
      Consensus CDS
      CCDS20101.2
      UniProtKB/TrEMBL
      Q3UZY6, Q8BR38
      Related
      ENSMUSP00000098989.5, ENSMUST00000101445.11
      Conserved Domains (8) summary
      cd07765
      Location:129 → 168
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
      smart00349
      Location:129 → 188
      KRAB; krueppel associated box
      COG5048
      Location:276 → 483
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:327 → 347
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:467 → 487
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:325 → 347
      zf-C2H2; Zinc finger, C2H2 type
      pfam12417
      Location:44 → 98
      DUF3669; Zinc finger protein
      pfam13465
      Location:396 → 420
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      47930324..47942234
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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