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    Fam184a family with sequence similarity 184, member A [ Mus musculus (house mouse) ]

    Gene ID: 75906, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Fam184aprovided by MGI
    Official Full Name
    family with sequence similarity 184, member Aprovided by MGI
    Primary source
    MGI:MGI:1923156
    See related
    Ensembl:ENSMUSG00000019856 AllianceGenome:MGI:1923156
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    3110012E06Rik; 4930438C08Rik; 4930589M24Rik
    Summary
    Is expressed in medulla oblongata; midbrain; midbrain mantle layer; and pons. Orthologous to human FAM184A (family with sequence similarity 184 member A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in frontal lobe adult (RPKM 8.0), testis adult (RPKM 5.7) and 11 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fam184a in Genome Data Viewer
    Location:
    10 B3; 10 27.26 cM
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (53509131..53627368, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (53633035..53751277, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_26696 Neighboring gene STARR-seq mESC enhancer starr_26698 Neighboring gene predicted gene, 40650 Neighboring gene predicted gene, 20597 Neighboring gene STARR-seq mESC enhancer starr_26699 Neighboring gene STARR-positive B cell enhancer ABC_E6844 Neighboring gene minichromosome maintenance 9 homologous recombination repair factor Neighboring gene STARR-positive B cell enhancer ABC_E10606 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:53349966-53350075 Neighboring gene anti-silencing function 1A histone chaperone Neighboring gene mannosidase 1, alpha Neighboring gene STARR-positive B cell enhancer mm9_chr10:53704763-53705064 Neighboring gene STARR-positive B cell enhancer ABC_E6845 Neighboring gene STARR-positive B cell enhancer mm9_chr10:53735714-53736015 Neighboring gene predicted gene, 53584 Neighboring gene STARR-positive B cell enhancer mm9_chr10:53795485-53795786 Neighboring gene predicted gene, 16998

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
    2. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in P-body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM184A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081428.2 → NP_001074897.1  protein FAM184A

      Status: VALIDATED

      Source sequence(s)
      AC153949, AC164581
      Consensus CDS
      CCDS35901.1
      UniProtKB/TrEMBL
      E9PW83, F6TU77
      Related
      ENSMUSP00000020003.8, ENSMUST00000020003.15
      Conserved Domains (2) summary
      TIGR02168
      Location:228 → 1005
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      53509131..53627368 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036156072.1 → XP_036011965.1  protein FAM184A isoform X17

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (2) summary
      COG1196
      Location:63 → 705
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    2. XM_017314135.3 → XP_017169624.1  protein FAM184A isoform X9

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (2) summary
      TIGR02168
      Location:263 → 1019
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    3. XM_006512897.5 → XP_006512960.1  protein FAM184A isoform X14

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (2) summary
      TIGR02168
      Location:263 → 1019
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    4. XM_030245348.2 → XP_030101208.1  protein FAM184A isoform X15

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (2) summary
      TIGR02168
      Location:228 → 1005
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    5. XM_006512893.5 → XP_006512956.1  protein FAM184A isoform X5

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (2) summary
      COG1196
      Location:163 → 1002
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    6. XM_006512890.5 → XP_006512953.1  protein FAM184A isoform X2

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (2) summary
      TIGR02168
      Location:263 → 1019
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    7. XM_006512894.5 → XP_006512957.1  protein FAM184A isoform X6

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (2) summary
      COG1196
      Location:163 → 988
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    8. XM_017314134.3 → XP_017169623.1  protein FAM184A isoform X7

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (3) summary
      COG1196
      Location:46 → 705
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:737 → 992
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    9. XM_006512889.5 → XP_006512952.1  protein FAM184A isoform X1

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (2) summary
      TIGR02168
      Location:263 → 1019
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    10. XM_011243225.4 → XP_011241527.1  protein FAM184A isoform X10

      UniProtKB/TrEMBL
      F6TU77
      Related
      ENSMUSP00000127400.2, ENSMUST00000163761.8
      Conserved Domains (3) summary
      COG1196
      Location:46 → 704
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:611 → 978
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    11. XM_030245350.2 → XP_030101210.1  protein FAM184A isoform X21

      Conserved Domains (2) summary
      COG1196
      Location:47 → 313
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:127 → 515
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    12. XM_006512898.5 → XP_006512961.1  protein FAM184A isoform X18

      UniProtKB/TrEMBL
      F6RSY8
      Conserved Domains (2) summary
      TIGR02168
      Location:46 → 628
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      TIGR02169
      Location:127 → 331
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    13. XM_030245349.2 → XP_030101209.1  protein FAM184A isoform X19

      UniProtKB/TrEMBL
      F6RSY8
      Related
      ENSMUSP00000130315.2, ENSMUST00000171807.8
      Conserved Domains (1) summary
      COG1196
      Location:258 → 646
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    14. XM_006512891.5 → XP_006512954.1  protein FAM184A isoform X3

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (2) summary
      TIGR02168
      Location:263 → 1019
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    15. XM_017314133.3 → XP_017169622.1  protein FAM184A isoform X4

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (2) summary
      TIGR02168
      Location:228 → 1005
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    16. XM_036156073.1 → XP_036011966.1  protein FAM184A isoform X20

      UniProtKB/TrEMBL
      F6RSY8
      Conserved Domains (1) summary
      COG1196
      Location:47 → 313
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    17. XM_017314136.3 → XP_017169625.1  protein FAM184A isoform X12

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (2) summary
      TIGR02168
      Location:228 → 1005
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    18. XM_006512896.5 → XP_006512959.1  protein FAM184A isoform X13

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (2) summary
      TIGR02168
      Location:263 → 1019
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    19. XM_006512895.5 → XP_006512958.1  protein FAM184A isoform X8

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (2) summary
      TIGR02168
      Location:263 → 1019
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    20. XM_036156071.1 → XP_036011964.1  protein FAM184A isoform X16

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (2) summary
      COG1196
      Location:163 → 988
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    21. XM_030245346.2 → XP_030101206.1  protein FAM184A isoform X11

      UniProtKB/TrEMBL
      F6TU77
      Conserved Domains (2) summary
      TIGR02168
      Location:228 → 1005
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam15665
      Location:57 → 267
      FAM184; Family with sequence similarity 184, A and B

    RNA

    1. XR_003948817.2 RNA Sequence

    2. XR_380088.5 RNA Sequence

    3. XR_004936297.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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