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Evi2 ecotropic viral integration site 2 [ Mus musculus (house mouse) ]

Gene ID: 101488212, updated on 8-Feb-2024

Summary

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Official Symbol
Evi2provided by MGI
Official Full Name
ecotropic viral integration site 2provided by MGI
Primary source
MGI:MGI:5439444
See related
AllianceGenome:MGI:5439444
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm21975; Evi2a-evi2b
Summary
This locus represents naturally occurring readthrough transcription between the neighboring Evi2a (ecotropic viral integration site 2a) and Evi2b (ecotropic viral integration site 2b) genes on chromosome 11. The readthrough transcript encodes a protein identical to that of the downstream gene product. [provided by RefSeq, May 2013]
Expression
Broad expression in spleen adult (RPKM 20.8), thymus adult (RPKM 14.9) and 18 other tissues See more
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Genomic context

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See Evi2 in Genome Data Viewer
Location:
11 B5; 11
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (79404211..79421435, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (79513385..79530609, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene neurofibromin 1 Neighboring gene STARR-seq mESC enhancer starr_30120 Neighboring gene expressed sequence AU040972 Neighboring gene STARR-positive B cell enhancer ABC_E8431 Neighboring gene STARR-positive B cell enhancer ABC_E7024 Neighboring gene STARR-positive B cell enhancer ABC_E5254 Neighboring gene STARR-positive B cell enhancer ABC_E11485 Neighboring gene oligodendrocyte myelin glycoprotein Neighboring gene ecotropic viral integration site 2b Neighboring gene ecotropic viral integration site 2a Neighboring gene STARR-positive B cell enhancer ABC_E11768 Neighboring gene RAB11 family interacting protein 4 (class II) Neighboring gene RAB11 family interacting protein 4 (class II), opposite strand 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:79428461-79428644 Neighboring gene predicted gene, 23293

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. Zanivan S, et al. J Proteome Res, 2008 Dec. PMID 19367708
  2. Large-scale phosphorylation analysis of mouse liver. Villén J, et al. Proc Natl Acad Sci U S A, 2007 Jan 30. PMID 17242355, Free PMC Article
  3. Lineage-specific biology revealed by a finished genome assembly of the mouse. Church DM, et al. PLoS Biol, 2009 May 5. PMID 19468303, Free PMC Article
  4. The phagosomal proteome in interferon-gamma-activated macrophages. Trost M, et al. Immunity, 2009 Jan 16. PMID 19144319
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Readthrough Evi2

Included genes: Evi2a, Evi2b

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in positive regulation of granulocyte differentiation ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein EVI2B
Names
Evi2a-Evi2b readthrough
ecotropic viral integration site 2B protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146023.4 → NP_666135.1  protein EVI2B precursor

    See identical proteins and their annotated locations for NP_666135.1

    Status: VALIDATED

    Source sequence(s)
    AK034440, AL591174
    UniProtKB/Swiss-Prot
    Q3U1A3, Q8VD58
    Conserved Domains (1) summary
    PRK13335
    Location:32 → 169
    PRK13335; superantigen-like protein; Reviewed

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    79404211..79421435 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8VD58.1 GenPept UniProtKB/Swiss-Prot:Q8VD58

Gene LinkOut

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