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Gon7 GON7 subunit of KEOPS complex [ Mus musculus (house mouse) ]

Gene ID: 100233175, updated on 8-Feb-2024

Summary

Official Symbol
Gon7provided by MGI
Official Full Name
GON7 subunit of KEOPS complexprovided by MGI
Primary source
MGI:MGI:4845848
See related
Ensembl:ENSMUSG00000091931 AllianceGenome:MGI:4845848
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of EKC/KEOPS complex. Orthologous to human GON7 (GON7 subunit of KEOPS complex). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 14.8), CNS E14 (RPKM 10.5) and 28 other tissues See more
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Genomic context

Location:
12 E; 12 52.14 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (102719534..102724069, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (102753275..102757810, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9862 Neighboring gene STARR-positive B cell enhancer ABC_E9390 Neighboring gene predicted gene 20604 Neighboring gene modulator of apoptosis 1 Neighboring gene lysosomal enzyme trafficking factor Neighboring gene STARR-seq mESC enhancer starr_33118 Neighboring gene STARR-seq mESC enhancer starr_33119 Neighboring gene ubiquitin protein ligase E3 component n-recognin 7 (putative) Neighboring gene BTB domain containing 7 Neighboring gene cytochrome c oxidase subunit 7C, mitochondrial pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Readthrough Gm20604

Readthrough gene: Gm20604, Included gene: Moap1

Potential readthrough

Included gene: Itpk1

Clone Names

  • MGC25937, MGC60472

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in tRNA threonylcarbamoyladenosine modification ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of EKC/KEOPS complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of EKC/KEOPS complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
EKC/KEOPS complex subunit GON7
Names
GON7, KEOPS complex subunit homolog
uncharacterized protein C14orf142 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142938.1NP_001136410.1  EKC/KEOPS complex subunit GON7

    See identical proteins and their annotated locations for NP_001136410.1

    Status: VALIDATED

    Source sequence(s)
    AC132315, AK010878
    Consensus CDS
    CCDS49148.1
    UniProtKB/Swiss-Prot
    P0C8B4
    Related
    ENSMUSP00000136425.2, ENSMUST00000173969.2
    Conserved Domains (1) summary
    pfam15387
    Location:396
    DUF4611; Domain of unknown function (DUF4611)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    102719534..102724069 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)