6OL9: Structure of the M5 muscarinic acetylcholine receptor (M5-T4L) bound to tiotropium

PDB ID: 6OL9Download
MMDB ID: 182114
PDB Deposition Date: 2019/4/16
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.541  Å
Source Organism:
Similar Structures:
Biological Unit for 6OL9: monomeric; determined by author and by software (PISA)
Molecular Components in 6OL9
Label Count Molecule
Protein (1 molecule)
1
Muscarinic Acetylcholine Receptor M5, T4 Lysozyme Fusion
(Gene symbol: CHRM5)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
OLEIC ACIDOLEIC ACID
2
1
(1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane(1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane
3
1
3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL
4
1
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303