8AW2: Mouse serotonin 5-HT3A receptor in complex with vortioxetine

PDB ID: 8AW2Download
MMDB ID: 243495
PDB Deposition Date: 2022/8/29
Updated in MMDB: 2024/05
Experimental Method:
electron microscopy
Resolution: 3.01  Å
Source Organism:
Similar Structures:
Biological Unit for 8AW2: pentameric; determined by author
Molecular Components in 8AW2
Label Count Molecule
Proteins (5 molecules)
5
5-hydroxytryptamine Receptor 3A
(Gene symbol: Htr3a)
Molecule annotation
Chemicals and Non-standard biopolymers (40 molecules)
1
25
2-acetamido-2-deoxy-beta-D-glucopyranose (Link to PubChem not yet available)2-acetamido-2-deoxy-beta-D-glucopyranose
2
5
beta-D-mannopyranose (Link to PubChem not yet available)beta-D-mannopyranose
3
5
CHLORIDE ION (Link to PubChem not yet available)CHLORIDE ION
4
5
Vortioxetine (Link to PubChem not yet available)Vortioxetine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303