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    OR56A3 olfactory receptor family 56 subfamily A member 3 [ Homo sapiens (human) ]

    Gene ID: 390083, updated on 5-Mar-2024

    Summary

    Official Symbol
    OR56A3provided by HGNC
    Official Full Name
    olfactory receptor family 56 subfamily A member 3provided by HGNC
    Primary source
    HGNC:HGNC:14786
    See related
    Ensembl:ENSG00000184478 AllianceGenome:HGNC:14786
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OR56A6; OR56A2P; OR56A3P
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
    Orthologs
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    Genomic context

    Location:
    11p15.4
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (5942251..6022010)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (6000747..6080512)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (5963481..5972577)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112268071 Neighboring gene olfactory receptor family 52 subfamily E member 5 Neighboring gene olfactory receptor family 52 subfamily Q member 1 pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:5943920-5945119 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:5949120-5950319 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:5958637-5959836 Neighboring gene olfactory receptor family 56 subfamily A member 5 Neighboring gene uncharacterized LOC124902621 Neighboring gene olfactory receptor family 52 subfamily L member 1 Neighboring gene keratin 18 pseudogene 58 Neighboring gene olfactory receptor family 56 subfamily A member 4 Neighboring gene uncharacterized LOC107984303 Neighboring gene RNA, 5S ribosomal pseudogene 329 Neighboring gene olfactory receptor family 56 subfamily A member 1 Neighboring gene olfactory receptor family 56 subfamily A member 7 pseudogene Neighboring gene olfactory receptor family 52 subfamily L member 2 pseudogene

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    olfactory receptor 56A3
    Names
    olfactory receptor 56A6
    olfactory receptor OR11-51
    olfactory receptor, family 56, subfamily A, member 2 pseudogene
    olfactory receptor, family 56, subfamily A, member 3 pseudogene
    olfactory receptor, family 56, subfamily A, member 6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003443.3NP_001003443.2  olfactory receptor 56A3

      See identical proteins and their annotated locations for NP_001003443.2

      Status: VALIDATED

      Source sequence(s)
      AC025016
      Consensus CDS
      CCDS41614.1
      UniProtKB/Swiss-Prot
      A6NN77, Q6IFF7, Q8NH54
      UniProtKB/TrEMBL
      A0A126GWL6
      Related
      ENSP00000493059.1, ENST00000641160.1
      Conserved Domains (2) summary
      pfam00001
      Location:46296
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:46311
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      5942251..6022010
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047426926.1XP_047282882.1  olfactory receptor 56A3 isoform X1

      UniProtKB/Swiss-Prot
      A6NN77, Q6IFF7, Q8NH54
      UniProtKB/TrEMBL
      A0A126GWL6

    RNA

    1. XR_007062481.1 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      6000747..6080512
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054368741.1XP_054224716.1  olfactory receptor 56A3 isoform X1

      UniProtKB/TrEMBL
      A0A126GVG2

    RNA

    1. XR_007082413.1 RNA Sequence