DataSet Record GDS5364: Expression Profiles Data Analysis Tools Sample Subsets
Title: BET inhibitor I-BET726 effect on MYCN-amplified neuroblastoma cell line CHP-212: dose response
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Summary: Analysis of CHP-212 neuroblastoma (NB) cells treated with 0.1 or 1 uM I-BET726, a BET inhibitor. MYCN is amplified in CHP-212. BET inhibitors display anti-proliferative activity in MYC driven hematologic cancer models. Results provide insight into the anti-proliferative activity of I-BET726 in NB.
Organism: Homo sapiens
Platform: GPL10558: Illumina HumanHT-12 V4.0 expression beadchip
Citation:
  • Wyce A, Ganji G, Smitheman KN, Chung CW et al. BET inhibition silences expression of MYCN and BCL2 and induces cytotoxicity in neuroblastoma tumor models. PLoS One 2013;8(8):e72967. PMID: 24009722
Reference Series: GSE47386 Sample count: 9
Value type: transformed count Series published: 2013/08/23