DataSet Record GDS4151: Expression Profiles Data Analysis Tools Sample Subsets
Title: Non-phosphorylated FTY720 effect on immortalized microglia HMO6 cell line
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Summary: Analysis of immortalized brain HMO6 microglia treated with FTY720-non-P, a non-phosphorylated form of FTY720 (a synthetic analog of sphingosine). Results provide insight into the molecular mechanisms responsible for triggering FTY720-non-P-induced apoptosis of HMO6.
Organism: Homo sapiens
Platform: GPL6244: [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
  • Yoshino T, Tabunoki H, Sugiyama S, Ishii K et al. Non-phosphorylated FTY720 induces apoptosis of human microglia by activating SREBP2. Cell Mol Neurobiol 2011 Oct;31(7):1009-20. PMID: 21519925
Reference Series: GSE28642 Sample count: 4
Value type: transformed count Series published: 2011/04/16