Pulmonary microvascular endothelial cell response to hypoxia in vitro: time course
Summary:
Analysis of pulmonary microvascular endothelial cells subjected to hypoxia for up to 48 hours. Pulmonary hypoxia is a common complication of chronic lung diseases leading to the development of pulmonary hypertension. Results provide insight into the molecular pathogenesis of pulmonary hypertension.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Costello CM, Howell K, Cahill E, McBryan J et al. Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 2008 Aug;295(2):L272-84. PMID: 18469115