Tumor necrosis factor effect in the absence of NF-kappaB activity: time course
Summary:
Temporal analysis of the effect of tumor necrosis factor (TNF) on gene expression in HeLa cells with NF-kappaB inactivated. NF-kappaB inactivated with 2 ug/ml doxycycline. Cells examined at various time points following stimulation with 25 ng/ml TNF. Results identify potential targets of NF-kappaB.
GPL8300:
[HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array
Citation:
Tian B, Nowak DE, Jamaluddin M, Wang S et al. Identification of direct genomic targets downstream of the nuclear factor-kappaB transcription factor mediating tumor necrosis factor signaling. J Biol Chem 2005 Apr 29;280(17):17435-48. PMID: 15722553
