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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1972 1
1974 2
1975 3
1978 2
1981 2
1982 1
1983 1
1984 1
1985 1
1986 1
1987 1
1988 8
1989 2
1990 3
1991 4
1992 7
1993 4
1994 5
1995 1
1996 6
1997 4
1998 4
1999 5
2000 6
2001 8
2002 7
2003 9
2004 8
2005 8
2006 6
2007 8
2008 14
2009 13
2010 11
2011 6
2012 10
2013 13
2014 14
2015 13
2016 9
2017 9
2018 4
2019 8
2020 11
2021 11
2022 11
2023 7
2024 3

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270 results

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Page 1
Genetic pain loss disorders.
Lischka A, Lassuthova P, Çakar A, Record CJ, Van Lent J, Baets J, Dohrn MF, Senderek J, Lampert A, Bennett DL, Wood JN, Timmerman V, Hornemann T, Auer-Grumbach M, Parman Y, Hübner CA, Elbracht M, Eggermann K, Geoffrey Woods C, Cox JJ, Reilly MM, Kurth I. Lischka A, et al. Nat Rev Dis Primers. 2022 Jun 16;8(1):41. doi: 10.1038/s41572-022-00365-7. Nat Rev Dis Primers. 2022. PMID: 35710757 Review.
Genetic pain loss includes congenital insensitivity to pain (CIP), hereditary sensory neuropathies and, if autonomic nerves are involved, hereditary sensory and autonomic neuropathy (HSAN). ...Conversely, chronic pain remains one of the greatest unreso …
Genetic pain loss includes congenital insensitivity to pain (CIP), hereditary sensory neuropathies and, if autonomic ne …
Diabetic Peripheral Neuropathy: Diagnosis and Treatment.
Røikjer J, Mørch CD, Ejskjaer N. Røikjer J, et al. Curr Drug Saf. 2021;16(1):2-16. doi: 10.2174/1574886315666200731173113. Curr Drug Saf. 2021. PMID: 32735526 Review.
Damage to the large fibres can be detected using nerve conduction studies (NCS) and often results in a significant reduction in sensitivity and loss of protective sensation, while damage to the small fibres is hard to reliably detect and can be either asymptomatic, associated wit …
Damage to the large fibres can be detected using nerve conduction studies (NCS) and often results in a significant reduction in sensitivity …
The physiological function of different voltage-gated sodium channels in pain.
Goodwin G, McMahon SB. Goodwin G, et al. Nat Rev Neurosci. 2021 May;22(5):263-274. doi: 10.1038/s41583-021-00444-w. Epub 2021 Mar 29. Nat Rev Neurosci. 2021. PMID: 33782571 Review.
Evidence from human genetic pain disorders shows that voltage-gated sodium channel alpha-subtypes Nav1.7, Nav1.8 and Nav1.9 are important in the peripheral signalling of pain. Nav1.7 is of particular interest because individuals with Nav1.7 loss-of-function mutation …
Evidence from human genetic pain disorders shows that voltage-gated sodium channel alpha-subtypes Nav1.7, Nav1.8 and Nav1.9 are impor …
Symptomatic treatments for amyotrophic lateral sclerosis/motor neuron disease.
Ng L, Khan F, Young CA, Galea M. Ng L, et al. Cochrane Database Syst Rev. 2017 Jan 10;1(1):CD011776. doi: 10.1002/14651858.CD011776.pub2. Cochrane Database Syst Rev. 2017. PMID: 28072907 Free PMC article. Review.
It is important to recognise that clinical trials may fail to demonstrate efficacy of an intervention for reasons other than a true lack of efficacy, for example because of insufficient statistical power, the wrong choice of dose, insensitive outcome measures or inappropri …
It is important to recognise that clinical trials may fail to demonstrate efficacy of an intervention for reasons other than a true lack of …
Endogenous opiates and behavior: 2022.
Bodnar RJ. Bodnar RJ. Peptides. 2023 Nov;169:171095. doi: 10.1016/j.peptides.2023.171095. Epub 2023 Sep 12. Peptides. 2023. PMID: 37704079 Review.
The review is subdivided into the following specific topics: molecular-biochemical effects and neurochemical localization studies of endogenous opioids and their receptors (1), the roles of these opioid peptides and receptors in pain and analgesia in animals (2) and humans …
The review is subdivided into the following specific topics: molecular-biochemical effects and neurochemical localization studies of endogen …
Endogenous opiates and behavior: 2021.
Bodnar RJ. Bodnar RJ. Peptides. 2023 Jun;164:171004. doi: 10.1016/j.peptides.2023.171004. Epub 2023 Mar 27. Peptides. 2023. PMID: 36990387 Review.
The review is subdivided into the following specific topics: molecular-biochemical effects and neurochemical localization studies of endogenous opioids and their receptors (1), the roles of these opioid peptides and receptors in pain and analgesia in animals (2) and humans …
The review is subdivided into the following specific topics: molecular-biochemical effects and neurochemical localization studies of endogen …
HEME: a neglected player in nociception?
Chiabrando D, Fiorito V, Petrillo S, Bertino F, Tolosano E. Chiabrando D, et al. Neurosci Biobehav Rev. 2021 May;124:124-136. doi: 10.1016/j.neubiorev.2021.01.011. Epub 2021 Feb 2. Neurosci Biobehav Rev. 2021. PMID: 33545213 Review.
The recent discovery of novel pathways associated with pain insensitivity in humans represents a unique opportunity to improve our knowledge on the pathophysiology of pain. ...Of note, alteration of heme metabolism has been associated with pain inse …
The recent discovery of novel pathways associated with pain insensitivity in humans represents a unique opportunity to improve …
Endogenous opiates and behavior: 2019.
Bodnar RJ. Bodnar RJ. Peptides. 2021 Jul;141:170547. doi: 10.1016/j.peptides.2021.170547. Epub 2021 Apr 5. Peptides. 2021. PMID: 33831447 Review.
The review is subdivided into the following specific topics: molecular-biochemical effects and neurochemical localization studies of endogenous opioids and their receptors (1), the roles of these opioid peptides and receptors in pain and analgesia in animals (2) and humans …
The review is subdivided into the following specific topics: molecular-biochemical effects and neurochemical localization studies of endogen …
Endogenous Opiates and Behavior: 2018.
Bodnar RJ. Bodnar RJ. Peptides. 2020 Oct;132:170348. doi: 10.1016/j.peptides.2020.170348. Epub 2020 Jun 20. Peptides. 2020. PMID: 32574695 Review.
The review is subdivided into the following specific topics: molecular-biochemical effects and neurochemical localization studies of endogenous opioids and their receptors (2), the roles of these opioid peptides and receptors in pain and analgesia in animals (3) and humans …
The review is subdivided into the following specific topics: molecular-biochemical effects and neurochemical localization studies of endogen …
PRDM12: New Opportunity in Pain Research.
Imhof S, Kokotović T, Nagy V. Imhof S, et al. Trends Mol Med. 2020 Oct;26(10):895-897. doi: 10.1016/j.molmed.2020.07.007. Epub 2020 Aug 20. Trends Mol Med. 2020. PMID: 32828702 Free article. Review.
PRDM12 is a newly identified causative gene for a type of congenital insensitivity to pain disorder, which is characterized by the inability to perceive pain. Here, we discuss the (patho)physiology of PRDM12 function and the opportunities and challenges those …
PRDM12 is a newly identified causative gene for a type of congenital insensitivity to pain disorder, which is characterized by …
270 results