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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 1
2006 2
2007 1
2008 1
2009 1
2010 2
2011 1
2014 1
2017 1
2018 3
2019 5
2020 3
2022 1
2024 0

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22 results

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Page 1
Low-Phospholipid Associated Cholelithiasis (LPAC) syndrome: A synthetic review.
Goubault P, Brunel T, Rode A, Bancel B, Mohkam K, Mabrut JY. Goubault P, et al. J Visc Surg. 2019 Sep;156(4):319-328. doi: 10.1016/j.jviscsurg.2019.02.006. Epub 2019 Mar 26. J Visc Surg. 2019. PMID: 30922600 Free article. Review.
Low-Phospholipid Associated Cholelithiasis (LPAC) is a genetic disease responsible for the development of intrahepatic lithiasis. It is associated with a mutation of the ABCB4 gene which codes for protein MDR3, a biliary carrier. ...
Low-Phospholipid Associated Cholelithiasis (LPAC) is a genetic disease responsible for the development of intrah …
Genetics of gallstone disease.
Rebholz C, Krawczyk M, Lammert F. Rebholz C, et al. Eur J Clin Invest. 2018 Jul;48(7):e12935. doi: 10.1111/eci.12935. Epub 2018 May 9. Eur J Clin Invest. 2018. PMID: 29635711 Review.
A smaller group of patients might develop gallstones primarily due low phosphatidylcholine concentrations in bile as a result of loss-of-function mutations of the ABCB4 transporter (low phospholipid-associated cholelithiasis syndrome). ...As res …
A smaller group of patients might develop gallstones primarily due low phosphatidylcholine concentrations in bile as a result of loss …
Genetic Analysis of ABCB4 Mutations and Variants Related to the Pathogenesis and Pathophysiology of Low Phospholipid-Associated Cholelithiasis.
Wang HH, Portincasa P, Liu M, Wang DQ. Wang HH, et al. Genes (Basel). 2022 Jun 11;13(6):1047. doi: 10.3390/genes13061047. Genes (Basel). 2022. PMID: 35741809 Free PMC article. Review.
Clinical studies have revealed that the ABCB4 gene encodes the phospholipid transporter on the canalicular membrane of hepatocytes, and its mutations and variants are the genetic basis of low phospholipid-associated cholelithiasis (LPAC), a rare …
Clinical studies have revealed that the ABCB4 gene encodes the phospholipid transporter on the canalicular membrane of hepatocytes, a …
Low phospholipid associated cholelithiasis: association with mutation in the MDR3/ABCB4 gene.
Rosmorduc O, Poupon R. Rosmorduc O, et al. Orphanet J Rare Dis. 2007 Jun 11;2:29. doi: 10.1186/1750-1172-2-29. Orphanet J Rare Dis. 2007. PMID: 17562004 Free PMC article. Review.
Low phospholipid-associated cholelithiasis (LPAC) is characterized by the association of ABCB4 mutations and low biliary phospholipid concentration with symptomatic and recurring cholelithiasis. ...The patients with the LPAC …
Low phospholipid-associated cholelithiasis (LPAC) is characterized by the association of ABCB4 mutations …
Molecular pathogenesis of hepatolithiasis--a type of low phospholipid-associated cholelithiasis.
Shoda J, Inada Y, Osuga T. Shoda J, et al. Front Biosci. 2006 Jan 1;11:669-75. doi: 10.2741/1826. Front Biosci. 2006. PMID: 16146760 Review.
In this review, the up-to-date data on the molecular pathogenesis of hepatolithiasis with special reference to a defect in phospholipid metabolism are introduced and discussed. Furthermore, a potential medical treatment targeting hepatic phospholipid transporters is …
In this review, the up-to-date data on the molecular pathogenesis of hepatolithiasis with special reference to a defect in phospholipid …
ABCB4 disease: Many faces of one gene deficiency.
Sticova E, Jirsa M. Sticova E, et al. Ann Hepatol. 2020 Mar-Apr;19(2):126-133. doi: 10.1016/j.aohep.2019.09.010. Epub 2019 Oct 31. Ann Hepatol. 2020. PMID: 31759867 Free article. Review.
Well-established phenotypes of ABCB4 deficit are: progressive familial intrahepatic cholestasis type 3, gallbladder disease 1 (syn. low phospholipid associated cholelithiasis syndrome), high -glutamyl transferase intrahepatic cholestasis of pregnancy, …
Well-established phenotypes of ABCB4 deficit are: progressive familial intrahepatic cholestasis type 3, gallbladder disease 1 (syn. low …
Familial intrahepatic cholestasis: New and wide perspectives.
Vitale G, Gitto S, Vukotic R, Raimondi F, Andreone P. Vitale G, et al. Dig Liver Dis. 2019 Jul;51(7):922-933. doi: 10.1016/j.dld.2019.04.013. Epub 2019 May 16. Dig Liver Dis. 2019. PMID: 31105019 Review.
Benign Intrahepatic Cholestasis, Intrahepatic Cholestasis of Pregnancy and Low-phospholipid-associated cholelithiasis involve the same genes and are characterized by intermittent attacks of cholestasis, no progression to cirrhosis, reversible pregnancy …
Benign Intrahepatic Cholestasis, Intrahepatic Cholestasis of Pregnancy and Low-phospholipid-associated cholelithiasi …
Variants in ABCB4 (MDR3) across the spectrum of cholestatic liver diseases in adults.
Stättermayer AF, Halilbasic E, Wrba F, Ferenci P, Trauner M. Stättermayer AF, et al. J Hepatol. 2020 Sep;73(3):651-663. doi: 10.1016/j.jhep.2020.04.036. Epub 2020 May 4. J Hepatol. 2020. PMID: 32376413 Free article. Review.
The ATP binding cassette subfamily B member 4 (ABCB4) gene on chromosome 7 encodes the ABCB4 protein (alias multidrug resistance protein 3 [MDR3]), a P-glycoprotein in the canalicular membrane of the hepatocytes that acts as a translocator of phospholipids into bile. Sever …
The ATP binding cassette subfamily B member 4 (ABCB4) gene on chromosome 7 encodes the ABCB4 protein (alias multidrug resistance protein 3 [ …
Molecular mechanisms for biliary phospholipid and drug efflux mediated by ABCB4 and bile salts.
Morita SY, Terada T. Morita SY, et al. Biomed Res Int. 2014;2014:954781. doi: 10.1155/2014/954781. Epub 2014 Jul 15. Biomed Res Int. 2014. PMID: 25133187 Free PMC article. Review.
Among them, ABCB4, also called MDR3, is essential for the secretion of phospholipids from hepatocytes into bile. The biliary phospholipids are associated with bile salts and cholesterol in mixed micelles, thereby reducing the detergent activity and cytotoxici …
Among them, ABCB4, also called MDR3, is essential for the secretion of phospholipids from hepatocytes into bile. The biliary phosp …
ABCB4 Gene Aberrations in Human Liver Disease: An Evolving Spectrum.
Reichert MC, Lammert F. Reichert MC, et al. Semin Liver Dis. 2018 Nov;38(4):299-307. doi: 10.1055/s-0038-1667299. Epub 2018 Oct 24. Semin Liver Dis. 2018. PMID: 30357767 Review.
Several diseases including progressive familial intrahepatic cholestasis type 3 (PFIC3), low phospholipid-associated cholelithiasis (LPAC), a subgroup of patients developing intrahepatic cholestasis of pregnancy (ICP), drug-induced liver injury and chr …
Several diseases including progressive familial intrahepatic cholestasis type 3 (PFIC3), low phospholipid-associated …
22 results