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Subtypes and Mimics of Sepsis.
Kellum JA, Formeck CL, Kernan KF, Gómez H, Carcillo JA. Kellum JA, et al. Crit Care Clin. 2022 Apr;38(2):195-211. doi: 10.1016/j.ccc.2021.11.013. Crit Care Clin. 2022. PMID: 35369943 Review.
Sepsis is a heterogenous and imprecise syndrome that includes multiple phenotypes, some of which are amenable to specific therapies. ...Because sepsis is common, it is easy to overlook unusual causes of organ failure and succumb to confirmation bias about the nature of an …
Sepsis is a heterogenous and imprecise syndrome that includes multiple phenotypes, some of which are amenable to specific therapies. …
CFHR Gene Variations Provide Insights in the Pathogenesis of the Kidney Diseases Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy.
Zipfel PF, Wiech T, Stea ED, Skerka C. Zipfel PF, et al. J Am Soc Nephrol. 2020 Feb;31(2):241-256. doi: 10.1681/ASN.2019050515. Epub 2020 Jan 24. J Am Soc Nephrol. 2020. PMID: 31980588 Free PMC article. Review.
Sequence and copy number variations in the human CFHR-Factor H gene cluster comprising the complement genes CFHR1, CFHR2, CFHR3, CFHR4, CFHR5, and Factor H are linked to the human kidney diseases atypical hemolytic uremic syndrome (aHUS) and C3 glomeru …
Sequence and copy number variations in the human CFHR-Factor H gene cluster comprising the complement genes CFHR1, CFHR2, CFHR3, CFHR4, CFHR …
An international consensus approach to the management of atypical hemolytic uremic syndrome in children.
Loirat C, Fakhouri F, Ariceta G, Besbas N, Bitzan M, Bjerre A, Coppo R, Emma F, Johnson S, Karpman D, Landau D, Langman CB, Lapeyraque AL, Licht C, Nester C, Pecoraro C, Riedl M, van de Kar NC, Van de Walle J, Vivarelli M, Frémeaux-Bacchi V; HUS International. Loirat C, et al. Pediatr Nephrol. 2016 Jan;31(1):15-39. doi: 10.1007/s00467-015-3076-8. Epub 2015 Apr 11. Pediatr Nephrol. 2016. PMID: 25859752 Review.
Atypical hemolytic uremic syndrome (aHUS) emerged during the last decade as a disease largely of complement dysregulation. ...
Atypical hemolytic uremic syndrome (aHUS) emerged during the last decade as a disease largely of complement dysr …
Thrombotic microangiopathies of pregnancy: Differential diagnosis.
Gupta M, Feinberg BB, Burwick RM. Gupta M, et al. Pregnancy Hypertens. 2018 Apr;12:29-34. doi: 10.1016/j.preghy.2018.02.007. Epub 2018 Feb 16. Pregnancy Hypertens. 2018. PMID: 29674195 Review.
Thrombotic microangiopathy (TMA) disorders are characterized by microangiopathic hemolytic anemia, thrombocytopenia and end-organ injury. In pregnancy and postpartum, TMA is most commonly encountered with HELLP (hemolysis, elevated liver enzymes, low platelet count synd …
Thrombotic microangiopathy (TMA) disorders are characterized by microangiopathic hemolytic anemia, thrombocytopenia and end-organ inj …
Atypical hemolytic uremic syndrome.
Afshar-Kharghan V. Afshar-Kharghan V. Hematology Am Soc Hematol Educ Program. 2016 Dec 2;2016(1):217-225. doi: 10.1182/asheducation-2016.1.217. Hematology Am Soc Hematol Educ Program. 2016. PMID: 27913483 Free PMC article. Review.
Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA) that affects multiple organs and the kidneys in particular. aHUS can be sporadic or familial and is most commonly caused by dysregulation of the alternative compleme …
Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA) that affects multiple organs and …
Familial atypical hemolytic uremic syndrome: a review of its genetic and clinical aspects.
Bu F, Borsa N, Gianluigi A, Smith RJ. Bu F, et al. Clin Dev Immunol. 2012;2012:370426. doi: 10.1155/2012/370426. Epub 2012 Nov 8. Clin Dev Immunol. 2012. PMID: 23251215 Free PMC article. Review.
Atypical hemolytic uremic syndrome (aHUS) is a rare renal disease (two per one million in the USA) characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. Both sporadic (80% of cases) and familial (2 …
Atypical hemolytic uremic syndrome (aHUS) is a rare renal disease (two per one million in the USA) characterized …
Atypical hemolytic uremic syndrome.
Loirat C, Frémeaux-Bacchi V. Loirat C, et al. Orphanet J Rare Dis. 2011 Sep 8;6:60. doi: 10.1186/1750-1172-6-60. Orphanet J Rare Dis. 2011. PMID: 21902819 Free PMC article. Review.
Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia, thrombocytopenia and renal impairment. ...Atypical HUS represents 5 -10% of HUS in children, but the majority of HUS in adults. ...
Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia, thrombocytopenia and ren …
Atypical Hemolytic Uremic Syndrome: New Challenges in the Complement Blockage Era.
Avila Bernabeu AI, Cavero Escribano T, Cao Vilarino M. Avila Bernabeu AI, et al. Nephron. 2020;144(11):537-549. doi: 10.1159/000508920. Epub 2020 Sep 18. Nephron. 2020. PMID: 32950988 Free article. Review.
Atypical hemolytic uremic syndrome (aHUS) is a rare cause of thrombotic microangiopathy (TMA), characterized by microangiopathic hemolytic anemia, consumptive thrombocytopenia, and multisystem end organ involvement, most commonly affecting the k …
Atypical hemolytic uremic syndrome (aHUS) is a rare cause of thrombotic microangiopathy (TMA), characterized by …
Atypical hemolytic uremic syndrome.
Kavanagh D, Goodship TH. Kavanagh D, et al. Curr Opin Hematol. 2010 Sep;17(5):432-8. doi: 10.1097/MOH.0b013e32833cae86. Curr Opin Hematol. 2010. PMID: 20613506 Review.
PURPOSE OF REVIEW: The last few years revealed a molecular distinction between thrombotic thrombocytopenic purpura, a disease characterized by a lack of ADAMTS13 activity, and atypical hemolytic uremic syndrome (aHUS), a disease of complement overactiv …
PURPOSE OF REVIEW: The last few years revealed a molecular distinction between thrombotic thrombocytopenic purpura, a disease characterized …
Factor H-related proteins.
Józsi M, Meri S. Józsi M, et al. Methods Mol Biol. 2014;1100:225-36. doi: 10.1007/978-1-62703-724-2_18. Methods Mol Biol. 2014. PMID: 24218263 Review.
Novel links between CFHRs and various diseases (C3 glomerulopathies, atypical hemolytic uremic syndrome and age-related macular degeneration) have been revealed in recent years, but we are still far from understanding their biological function....
Novel links between CFHRs and various diseases (C3 glomerulopathies, atypical hemolytic uremic syndrome and age- …
44 results