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PubMed for id: 28178861

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Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue.
Martinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Zihsler S, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, Lord JD, Garcia KC, Palmer TD, Steinman L, Nepom GT, Wight TN, Bollyky PL, Kuipers HF. Martinez HA, et al. Nat Commun. 2024 Feb 20;15(1):1564. doi: 10.1038/s41467-024-45012-9. Nat Commun. 2024. PMID: 38378682 Free PMC article.
Revisiting IL-2: Biology and therapeutic prospects.
Abbas AK, Trotta E, R Simeonov D, Marson A, Bluestone JA. Abbas AK, et al. Sci Immunol. 2018 Jul 6;3(25):eaat1482. doi: 10.1126/sciimmunol.aat1482. Sci Immunol. 2018. PMID: 29980618 Review.
IL-2 and Beyond in Cancer Immunotherapy.
Wrangle JM, Patterson A, Johnson CB, Neitzke DJ, Mehrotra S, Denlinger CE, Paulos CM, Li Z, Cole DJ, Rubinstein MP. Wrangle JM, et al. J Interferon Cytokine Res. 2018 Feb;38(2):45-68. doi: 10.1089/jir.2017.0101. J Interferon Cytokine Res. 2018. PMID: 29443657 Free PMC article. Review.
Interleukin-2: Biology, Design and Application.
Arenas-Ramirez N, Woytschak J, Boyman O. Arenas-Ramirez N, et al. Trends Immunol. 2015 Dec;36(12):763-777. doi: 10.1016/j.it.2015.10.003. Epub 2015 Nov 10. Trends Immunol. 2015. PMID: 26572555 Free article. Review.