PubMed (MeSH Keyword) for id: 16757019

Year	Number of Results
2006	2
2007	2
2008	1
2009	1
2011	3
2013	1
2014	4
2017	1
2020	1
2024	0

1

Design, Synthesis and Biological Evaluation of Highly Potent Simplified Archazolids.

Rivière S, Vielmuth C, Ennenbach C, Abdelrahman A, Lemke C, Gütschow M, Müller CE, Menche D. Rivière S, et al. ChemMedChem. 2020 Jul 20;15(14):1348-1363. doi: 10.1002/cmdc.202000154. Epub 2020 Jun 10. ChemMedChem. 2020. PMID: 32363789 Free PMC article.

2

Selective upregulation of TNFα expression in classically-activated human monocyte-derived macrophages (M1) through pharmacological interference with V-ATPase.

Thomas L, Rao Z, Gerstmeier J, Raasch M, Weinigel C, Rummler S, Menche D, Müller R, Pergola C, Mosig A, Werz O. Thomas L, et al. Biochem Pharmacol. 2017 Apr 15;130:71-82. doi: 10.1016/j.bcp.2017.02.004. Epub 2017 Feb 9. Biochem Pharmacol. 2017. PMID: 28189727 Free article.

3

Up-regulation of cholesterol associated genes as novel resistance mechanism in glioblastoma cells in response to archazolid B.

Hamm R, Zeino M, Frewert S, Efferth T. Hamm R, et al. Toxicol Appl Pharmacol. 2014 Nov 15;281(1):78-86. doi: 10.1016/j.taap.2014.08.033. Epub 2014 Sep 11. Toxicol Appl Pharmacol. 2014. PMID: 25218289

4

Resistance mechanisms of cancer cells to the novel vacuolar H(+)-ATPase inhibitor archazolid B.

Hamm R, Sugimoto Y, Steinmetz H, Efferth T. Hamm R, et al. Invest New Drugs. 2014 Oct;32(5):893-903. doi: 10.1007/s10637-014-0134-1. Epub 2014 Jul 29. Invest New Drugs. 2014. PMID: 25065443

5

Induction of cholesterol biosynthesis by archazolid B in T24 bladder cancer cells.

Hamm R, Chen YR, Seo EJ, Zeino M, Wu CF, Müller R, Yang NS, Efferth T. Hamm R, et al. Biochem Pharmacol. 2014 Sep 1;91(1):18-30. doi: 10.1016/j.bcp.2014.06.018. Epub 2014 Jun 26. Biochem Pharmacol. 2014. PMID: 24976507

6

V-ATPase inhibition by archazolid leads to lysosomal dysfunction resulting in impaired cathepsin B activation in vivo.

Kubisch R, Fröhlich T, Arnold GJ, Schreiner L, von Schwarzenberg K, Roidl A, Vollmar AM, Wagner E. Kubisch R, et al. Int J Cancer. 2014 May 15;134(10):2478-88. doi: 10.1002/ijc.28562. Epub 2013 Nov 14. Int J Cancer. 2014. PMID: 24166050 Free article.

7

Synthesis and activity of the archazolid western hemisphere.

Tran AB, Melly GC, Doucette R, Ashcraft B, Sebren LJ, Havko N, Young JC, O'Neil GW. Tran AB, et al. Org Biomol Chem. 2011 Oct 26;9(22):7671-4. doi: 10.1039/c1ob06446k. Epub 2011 Sep 20. Org Biomol Chem. 2011. PMID: 21931924

8

Archazolid A-15-O-β-D-glucopyranoside and iso-archazolid B: potent V-ATPase inhibitory polyketides from the myxobacteria Cystobacter violaceus and Archangium gephyra.

Horstmann N, Essig S, Bockelmann S, Wieczorek H, Huss M, Sasse F, Menche D. Horstmann N, et al. J Nat Prod. 2011 May 27;74(5):1100-5. doi: 10.1021/np200036v. Epub 2011 Apr 22. J Nat Prod. 2011. PMID: 21513292

9

Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase.

Capell A, Liebscher S, Fellerer K, Brouwers N, Willem M, Lammich S, Gijselinck I, Bittner T, Carlson AM, Sasse F, Kunze B, Steinmetz H, Jansen R, Dormann D, Sleegers K, Cruts M, Herms J, Van Broeckhoven C, Haass C. Capell A, et al. J Neurosci. 2011 Feb 2;31(5):1885-94. doi: 10.1523/JNEUROSCI.5757-10.2011. J Neurosci. 2011. PMID: 21289198 Free PMC article.

10

Modular total synthesis of archazolid A and B.

Menche D, Hassfeld J, Li J, Mayer K, Rudolph S. Menche D, et al. J Org Chem. 2009 Oct 2;74(19):7220-9. doi: 10.1021/jo901565n. J Org Chem. 2009. PMID: 19739663

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