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38709223,38665214,38646442,38590111,38583188,38452875,38440392,38367697,38362953,38321910,38319661,38315622,38274038,38262663,38251824,38243347,38225737,38198772,38195021,38099439,38074954,38063014,38044126,38038888,38037559,38016617,38007987,37994671,37940007,37937947,37883825,37807179,37776495,37752799,37702218,37659712,37650500,37643933,37578629,37554390,37526889,37524151,37452707,37359762,37276603,37189208,37164235,37161757,37099928,37071614,37012654,36998725,36980191,36951445,36931108,36841350,36819779,36801267,36788874,36781362,36745898,36745892,36745889,36705021,36648995,36641043,36631839,36608356,36463352,36419638,36365143,36334898,36288654,36241213,36184124,36177443,36111176,36090880,36060533,36052391,36034496,36000537,35854686,35792285,35785611,35772127,35756655,35679462,35678545,35578993,35556233,35543315,35530955,35509104,35493945,35443409,35435515,35435047,35419167,35405470,35355238,35313995,35309557,35300248,35260801,35145512,35128808,34986833,34925690,34896108,34855658,34806117,34773177,34737134,34719603,34673095,34595173,34529169,34507127,34491073,34486358,34431446,34385972,34373979,34331518,34328205,34311056,34275028,34273441,34248500,34158388,34140326,34136501,34121120,34042170,34025405,34012394,33991634,33986719,33983621,33913337,33853052,33801796,33755911,33735668,33648537,33641668,33578226,33551444,33547153,33470890,33423695,33407568,33335777,33335751,33332579,33263147,33256235,33245786,33222266,33171422,33132370,33122255,33112579,33106367,33087495,33058939,33004063,32999074,32983286,32969238,32912508,32734237,32675306,32602110,32557313,32549946,32539736,32351331,32323555,32307727,32224230,32190334,32072593,32072586,32072573,31999195,31875831,31862517,31846335,31833782,31823177,31812806,31784381,31742220,31681968,31645114,31637933,31586682,31565956,31562710,31500552,31490111,31490110,31490105,31470748,31443074,31358206,31208948,31184495,31165001,31155721,31151837,31142225,31002151,30910816,30870142,30796715,30642187,30634215,30630003,30562600,30524344,30486811,30454900,30395722,30381091,30348961,30340585,30236003,30235990,30235582,30235539,30224926,30222411,30205274,30128711,30104314,30068631,29948249,29859495,29786434,29714552,29679706,29593024,29541054,29411303,29403971,29086673,29061107,28954878,28822875,28799316,28716241,28685394,28683728,28679602,28636380,28537222,28525977,28385577,28380275,28293215,28216425,28096675,28028788,28000127,27988488,27933491,27842971,27668123,27385592,27373012,27295604,27229323,27150947,27046733,26903171,26877192,26858008,26567107,26519919,26401233,26307411,26300843,26248005,26233840,26232707,26224360,26220872,26162419,26091639,25711829,25668358,25619130,25580771,25328080,25227071,25175054,25105088,25029592,25023199,24962895,24850470,24801246,24639200,24562060,24482775,24450819,24401400,24388507,24265302,24265300,24146993,24121431,24000747,23981692,23896892,23786363,23743155,23719405,23665080,23378859,23263735,23230461,23205046,23170779,23138891,22984006,22905923,22897602,22619500,22381312,22300906,22274965,22165165,22145121,22046309,21996025,21859887,21757919,21725734,21563689,21414081,21376950,21337721,21251129,21107314,20939460,20638213,20570744,20536619,20465455,20406224,20359910,20159665,20135694,20109296,19922536,19915983,19853397,19767509,19740402,19726752,19722035,19631153,19382573,19378710,19319701,19182450,19129506,19099673,19096545,18958677,18958670,18840242,18781528,18677820,18670158,18438957,18289410,18199896,17868933,17719736,17706540,17631908,17543995,17524425,17523251,17370280,17323190,17317927,17290087,17015988,16959462,16904281,16872240,16806993,16723215,16338164,16231954,16212781,16174898,16089314,16076542,16011455,15975833,15961324,15934857,15889873,15813863,15691222,15533669,15517542,15467270,15337439,15154824,15093151,14738915,14703965,12835531,12756823,12644204,12613823,12497768,12486747,12388859,12325111,12297434,12084506,12031063,11710304,11600301,11523068,11471989,11450068,11366288,11283388,10964483,10777198,10745097,10566323,10494969,10416259,10394958,10367669,10365472,10365470,10354523,9809666,9689050,9641814,9507158,9464943,9387482,9224894,9148927,9030236,8911541,8780721,8702803,8087842,7813246,7797510,7552232,6400252,3701140,1726245,1606283,734778,38634270,38613810,38608476,38556140,38552289,38517368,38499232,38479036,38465865,38460801,38438086,38433011,38408556,38363572,38338716,38334240,38325841,38324982,38271077,38266580,38256178,38185989,38176227,38169640,38113759,38104695,38103398,38070317,38049769,38029236,38012465,38009316,37978512,37951389,37907028,37904677,37904612,37884088,37875357,37846812,37799085,37797431,37787451,37750297,37716905,37678549,37673200,37668963,37661186,37633650,37614138,37594575,37581399,37556585,37553782,37552127,37525083,37493922,37355236,37354351,37267801,37176030,37170723,37106065,37105375,37102432,37058973,36996813,36939977,36919939,36914055,36892712,36891905,36858814,36805044,36799223,36786944,36780760,36756894,36741373,36740252,36705426,36695309,36689811,36626786,36619742,36598532,36580209,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Results by year

Year	Number of Results
1978	1
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Page 1

Results from a Joined Prospective Study to Evaluate the Sensitivity of the In Vivo Dog QT Assay in Line with the ICH E14/S7B Q&A Best Practices.

Bétat AM, Delaunois A, Delpy E, Loiseau M, Maurin A, Poizat G, Possémé C, Weinelt F, Drieu la Rochelle C, Martel E, Valentin JP. Bétat AM, et al. Clin Pharmacol Ther. 2024 May 6. doi: 10.1002/cpt.3283. Online ahead of print. Clin Pharmacol Ther. 2024. PMID: 38709223

ICH S1 prospective evaluation study: weight of evidence approach to predict outcome and value of 2-year rat carcinogenicity studies. A report from the regulatory authorities subgroup.

Bourcier T, McGovern T, Cavaliero T, Ebere G, Nishikawa A, Nishimura J, Ogawa K, Pasanen M, Vespa A, Van der Laan JW. Bourcier T, et al. Front Toxicol. 2024 Apr 11;6:1353783. doi: 10.3389/ftox.2024.1353783. eCollection 2024. Front Toxicol. 2024. PMID: 38665214 Free PMC article.

Developing a pragmatic consensus procedure supporting the ICH S1B(R1) weight of evidence carcinogenicity assessment.

Bassan A, Steigerwalt R, Keller D, Beilke L, Bradley PM, Bringezu F, Brock WJ, Burns-Naas LA, Chambers J, Cross K, Dorato M, Elespuru R, Fuhrer D, Hall F, Hartke J, Jahnke GD, Kluxen FM, McDuffie E, Schmidt F, Valentin JP, Woolley D, Zane D, Myatt GJ. Bassan A, et al. Front Toxicol. 2024 Apr 5;6:1370045. doi: 10.3389/ftox.2024.1370045. eCollection 2024. Front Toxicol. 2024. PMID: 38646442 Free PMC article.

Comparison of stress hyperglycemia ratio and glycemic gap on acute ICH in-hospital outcomes.

Zhang J, Zhang Q, Gu H, Zhou Q, Li Z, Zhao X. Zhang J, et al. Ann Clin Transl Neurol. 2024 Apr 8. doi: 10.1002/acn3.52063. Online ahead of print. Ann Clin Transl Neurol. 2024. PMID: 38590111 Free article.

Rosiglitazone Promotes Microglial Distribution via Activation of PPARγ and CD36 in the ICH Rat Model.

Mu Q, He Q, Zhou H, Xu Y, Wu G. Mu Q, et al. Neuro Endocrinol Lett. 2024 Apr 7;45(2). Online ahead of print. Neuro Endocrinol Lett. 2024. PMID: 38583188

Open forum conference on the ICH M13A bioequivalence guideline.

Blume H, Wedemeyer S, Seidlitz A, Beuerle G, Klein S, Bilensoy E. Blume H, et al. Eur J Pharm Sci. 2024 May 1;196:106741. doi: 10.1016/j.ejps.2024.106741. Epub 2024 Mar 5. Eur J Pharm Sci. 2024. PMID: 38452875 Free article. Review.

Hypothermia and temperature modulation for intracerebral hemorrhage (ICH): pathophysiology and translational applications.

Cadena AJ, Rincon F. Cadena AJ, et al. Front Neurosci. 2024 Feb 19;18:1289705. doi: 10.3389/fnins.2024.1289705. eCollection 2024. Front Neurosci. 2024. PMID: 38440392 Free PMC article. Review.

Validation of a mouse 3D gastruloid-based embryotoxicity assay in reference to the ICH S5(R3) guideline chemical exposure list.

Huntsman MC, Kurashima CK, Marikawa Y. Huntsman MC, et al. Reprod Toxicol. 2024 Apr;125:108558. doi: 10.1016/j.reprotox.2024.108558. Epub 2024 Feb 15. Reprod Toxicol. 2024. PMID: 38367697

Scientific Review of the Proarrhythmic Risks of Oligonucleotide Therapeutics: Are Dedicated ICH S7B/E14 Studies Needed for Low-Risk Modalities?

Qu Y, Henderson KA, Harper TA Jr, Vargas HM. Qu Y, et al. Clin Pharmacol Ther. 2024 Feb 16. doi: 10.1002/cpt.3204. Online ahead of print. Clin Pharmacol Ther. 2024. PMID: 38362953

Nitrosamines, ICH Q3A-Q3E, Global Substance Registration System (GSRS), N-nitroso dimethyl amine (NDMA), Drug substance life cycle.

Bhirud D, Agrawal G, Shah H, Patel A, Palkar MB, Bhattacharya S, Prajapati BG. Bhirud D, et al. Curr Top Med Chem. 2024 Feb 6. doi: 10.2174/0115680266278636240125113509. Online ahead of print. Curr Top Med Chem. 2024. PMID: 38321910

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