PubMed (GeneRIF) for id: 23643

Year	Number of Results
2001	2
2002	2
2003	6
2004	6
2005	5
2006	5
2007	11
2008	12
2009	15
2010	14
2011	9
2012	4
2013	4
2014	10
2015	10
2016	3
2017	4
2018	3
2019	3
2020	1
2021	2
2022	1
2023	2
2024	2

1

Myeloid differentiation factor-2/LY96, a potential predictive biomarker of metastasis and poor outcomes in prostate cancer: clinical implications as a potential therapeutic target.

Ferrari MG, Jimenez-Uribe AP, Wang L, Hoeppner LH, Murugan P, Hahm E, Yu J, Kuzel TM, Gradilone SA, Mansini AP. Ferrari MG, et al. Oncogene. 2024 Feb;43(7):484-494. doi: 10.1038/s41388-023-02925-x. Epub 2023 Dec 23. Oncogene. 2024. PMID: 38135694 Free PMC article.

2

Insights into the molecular basis and mechanism of heme-triggered TLR4 signalling: The role of heme-binding motifs in TLR4 and MD2.

Hopp MT, Holze J, Lauber F, Holtkamp L, Rathod DC, Miteva MA, Prestes EB, Geyer M, Manoury B, Merle NS, Roumenina LT, Bozza MT, Weindl G, Imhof D. Hopp MT, et al. Immunology. 2024 Feb;171(2):181-197. doi: 10.1111/imm.13708. Epub 2023 Oct 26. Immunology. 2024. PMID: 37885279

3

Myeloid differentiation factor-2 activates monocytes in patients with dilated cardiomyopathy.

Feldtmann R, Kümmel A, Chamling B, Strohbach A, Lehnert K, Gross S, Loerzer L, Riad A, Lindner D, Westermann D, Fielitz J, Dörr M, Felix SB. Feldtmann R, et al. Immunology. 2022 Sep;167(1):40-53. doi: 10.1111/imm.13490. Epub 2022 Jun 29. Immunology. 2022. PMID: 35502635 Free article.

4

Soluble MD-2 and Heme in Sickle Cell Disease Plasma Promote Pro-Inflammatory Signaling in Endothelial Cells.

Zhang P, Nguyen J, Abdulla F, Nelson AT, Beckman JD, Vercellotti GM, Belcher JD. Zhang P, et al. Front Immunol. 2021 Mar 26;12:632709. doi: 10.3389/fimmu.2021.632709. eCollection 2021. Front Immunol. 2021. PMID: 33841413 Free PMC article.

5

Myeloid differentiation 2 deficiency attenuates AngII-induced arterial vascular oxidative stress, inflammation, and remodeling.

Huang S, You S, Qian J, Dai C, Shen S, Wang J, Huang W, Liang G, Wu G. Huang S, et al. Aging (Albany NY). 2021 Jan 20;13(3):4409-4427. doi: 10.18632/aging.202402. Epub 2021 Jan 20. Aging (Albany NY). 2021. PMID: 33495414 Free PMC article.

6

HIV-1 Tat - TLR4/MD2 interaction drives the expression of IDO-1 in monocytes derived dendritic cells through NF-κB dependent pathway.

Bahraoui E, Serrero M, Planès R. Bahraoui E, et al. Sci Rep. 2020 May 18;10(1):8177. doi: 10.1038/s41598-020-64847-y. Sci Rep. 2020. PMID: 32424165 Free PMC article.

7

Expression of human TLR4/myeloid differentiation factor 2 directs an early innate immune response associated with modest increases in bacterial burden during Coxiella burnetii infection.

Robison A, Snyder DT, Christensen K, Kimmel E, Hajjar AM, Jutila MA, Hedges JF. Robison A, et al. Innate Immun. 2019 Oct;25(7):401-411. doi: 10.1177/1753425919855420. Epub 2019 Jun 10. Innate Immun. 2019. PMID: 31180798 Free PMC article.

8

The effects and mechanisms of myeloid differentiation protein 2 on intestinal mucosal permeability in mice with chronic colitis.

Han C, Guan Q, Guo L, Yang Y, Ruan S, Zhang X. Han C, et al. J Cell Physiol. 2019 Nov;234(11):21089-21099. doi: 10.1002/jcp.28711. Epub 2019 Apr 29. J Cell Physiol. 2019. PMID: 31032920

9

Structural variants of Salmonella Typhimurium lipopolysaccharide induce less dimerization of TLR4/MD-2 and reduced pro-inflammatory cytokine production in human monocytes.

Aldapa-Vega G, Moreno-Eutimio MA, Berlanga-Taylor AJ, Jiménez-Uribe AP, Nieto-Velazquez G, López-Ortega O, Mancilla-Herrera I, Cortés-Malagón EM, Gunn JS, Isibasi A, Wong-Baeza I, López-Macías C, Pastelin-Palacios R. Aldapa-Vega G, et al. Mol Immunol. 2019 Jul;111:43-52. doi: 10.1016/j.molimm.2019.03.003. Epub 2019 Apr 6. Mol Immunol. 2019. PMID: 30959420 Free article.

10

Isofraxidin targets the TLR4/MD-2 axis to prevent osteoarthritis development.

Jin J , Yu X , Hu Z , Tang S , Zhong X , Xu J , Shang P , Huang Y , Liu H . Jin J , et al. Food Funct. 2018 Nov 14;9(11):5641-5652. doi: 10.1039/c8fo01445k. Food Funct. 2018. PMID: 30299441

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