PubMed for id: 9040

Year	Number of Results
1998	1
1999	1
2000	2
2001	1
2002	1
2003	2
2004	3
2005	4
2006	4
2007	5
2008	7
2009	8
2010	4
2011	7
2012	6
2013	5
2014	10
2015	8
2016	11
2017	11
2018	16
2019	11
2020	14
2021	11
2022	16
2023	7
2024	3

1

NEDD8-conjugating enzyme UBC12 as a novel therapeutic target in esophageal squamous cell carcinoma.

Wang S, Xian J, Li L, Jiang Y, Liu Y, Cai L, Hoffman RM, Jia L, Zhao H, Zhang Y. Wang S, et al. Signal Transduct Target Ther. 2020 Jul 10;5(1):123. doi: 10.1038/s41392-020-00226-3. Signal Transduct Target Ther. 2020. PMID: 32651357 Free PMC article. No abstract available.

2

UBE2M promotes cell proliferation via the β-catenin/cyclin D1 signaling in hepatocellular carcinoma.

Zhang GC, Yu XN, Sun JL, Xiong J, Yang YJ, Jiang XM, Zhu JM. Zhang GC, et al. Aging (Albany NY). 2020 Feb 3;12(3):2373-2392. doi: 10.18632/aging.102749. Epub 2020 Feb 3. Aging (Albany NY). 2020. PMID: 32012120 Free PMC article.

3

Polymorphisms in Genes Involved in EGFR Turnover Are Predictive for Cetuximab Efficacy in Colorectal Cancer.

Stintzing S, Zhang W, Heinemann V, Neureiter D, Kemmerling R, Kirchner T, Jung A, Folwaczny M, Yang D, Ning Y, Sebio A, Stremitzer S, Sunakawa Y, Matsusaka S, Yamauchi S, Loupakis F, Cremolini C, Falcone A, Lenz HJ. Stintzing S, et al. Mol Cancer Ther. 2015 Oct;14(10):2374-81. doi: 10.1158/1535-7163.MCT-15-0121. Epub 2015 Jul 23. Mol Cancer Ther. 2015. PMID: 26206335 Free PMC article.

4

Inactivating UBE2M impacts the DNA damage response and genome integrity involving multiple cullin ligases.

Cukras S, Morffy N, Ohn T, Kee Y. Cukras S, et al. PLoS One. 2014 Jul 15;9(7):e101844. doi: 10.1371/journal.pone.0101844. eCollection 2014. PLoS One. 2014. PMID: 25025768 Free PMC article.

5

Improvement of Oral Bioavailability of Pyrazolo-Pyridone Inhibitors of the Interaction of DCN1/2 and UBE2M.

Kim HS, Hammill JT, Scott DC, Chen Y, Rice AL, Pistel W, Singh B, Schulman BA, Guy RK. Kim HS, et al. J Med Chem. 2021 May 13;64(9):5850-5862. doi: 10.1021/acs.jmedchem.1c00035. Epub 2021 May 4. J Med Chem. 2021. PMID: 33945681 Free PMC article.

6

NPRL2 reduces the niraparib sensitivity of castration-resistant prostate cancer via interacting with UBE2M and enhancing neddylation.

Zhao X, Jiang L, Hu D, Tang Y, Zhao G, Du X, Luo S, Tang W. Zhao X, et al. Exp Cell Res. 2021 Jun 15;403(2):112614. doi: 10.1016/j.yexcr.2021.112614. Epub 2021 Apr 24. Exp Cell Res. 2021. PMID: 33905671

7

Ubiquitin conjugating enzyme E2 M promotes apoptosis in osteoarthritis chondrocytes via Wnt/β-catenin signaling.

Ba C, Ni X, Yu J, Zou G, Zhu H. Ba C, et al. Biochem Biophys Res Commun. 2020 Sep 3;529(4):970-976. doi: 10.1016/j.bbrc.2020.06.095. Epub 2020 Jul 30. Biochem Biophys Res Commun. 2020. PMID: 32819607

8

UBC12-mediated SREBP-1 neddylation worsens metastatic tumor prognosis.

Heo MJ, Kang SH, Kim YS, Lee JM, Yu J, Kim HR, Lim H, Kim KM, Jung J, Jeong LS, Moon A, Kim SG. Heo MJ, et al. Int J Cancer. 2020 Nov 1;147(9):2550-2563. doi: 10.1002/ijc.33113. Epub 2020 Jun 23. Int J Cancer. 2020. PMID: 32449166 Free article.

9

Targeting DCN1-UBC12 Protein-Protein Interaction for Regulation of Neddylation Pathway.

Zhou H, Lu J, Yang CY, Sun Y, Wang S. Zhou H, et al. Adv Exp Med Biol. 2020;1217:349-362. doi: 10.1007/978-981-15-1025-0_20. Adv Exp Med Biol. 2020. PMID: 31898237 Review.

10

Targeting the DCN1-UBC12 protein-protein interaction: novel approaches and future directions.

Fang Y, Yu B, Liao G, Liu HM. Fang Y, et al. Future Med Chem. 2019 Nov;11(22):2869-2871. doi: 10.4155/fmc-2019-0253. Epub 2019 Oct 31. Future Med Chem. 2019. PMID: 31668094 Free article. No abstract available.

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