PubMed for id: 439216

Year	Number of Results
2001	2
2002	2
2003	1
2004	4
2005	2
2006	4
2007	3
2008	5
2011	1
2015	1
2016	2
2017	1
2018	2
2019	1
2024	0

1

EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma.

Hübner JM, Müller T, Papageorgiou DN, Mauermann M, Krijgsveld J, Russell RB, Ellison DW, Pfister SM, Pajtler KW, Kool M. Hübner JM, et al. Neuro Oncol. 2019 Jul 11;21(7):878-889. doi: 10.1093/neuonc/noz058. Neuro Oncol. 2019. PMID: 30923826 Free PMC article.

2

Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding.

Chen S, Jiao L, Shubbar M, Yang X, Liu X. Chen S, et al. Mol Cell. 2018 Mar 1;69(5):840-852.e5. doi: 10.1016/j.molcel.2018.01.039. Mol Cell. 2018. PMID: 29499137 Free PMC article.

3

Structures of human PRC2 with its cofactors AEBP2 and JARID2.

Kasinath V, Faini M, Poepsel S, Reif D, Feng XA, Stjepanovic G, Aebersold R, Nogales E. Kasinath V, et al. Science. 2018 Feb 23;359(6378):940-944. doi: 10.1126/science.aar5700. Epub 2018 Jan 18. Science. 2018. PMID: 29348366 Free PMC article.

4

Mutations in genes encoding polycomb repressive complex 2 subunits cause Weaver syndrome.

Imagawa E, Higashimoto K, Sakai Y, Numakura C, Okamoto N, Matsunaga S, Ryo A, Sato Y, Sanefuji M, Ihara K, Takada Y, Nishimura G, Saitsu H, Mizuguchi T, Miyatake S, Nakashima M, Miyake N, Soejima H, Matsumoto N. Imagawa E, et al. Hum Mutat. 2017 Jun;38(6):637-648. doi: 10.1002/humu.23200. Epub 2017 Mar 15. Hum Mutat. 2017. PMID: 28229514

5

Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance.

Brooun A, Gajiwala KS, Deng YL, Liu W, Bolaños B, Bingham P, He YA, Diehl W, Grable N, Kung PP, Sutton S, Maegley KA, Yu X, Stewart AE. Brooun A, et al. Nat Commun. 2016 Apr 28;7:11384. doi: 10.1038/ncomms11384. Nat Commun. 2016. PMID: 27122193 Free PMC article.

6

Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.

Justin N, Zhang Y, Tarricone C, Martin SR, Chen S, Underwood E, De Marco V, Haire LF, Walker PA, Reinberg D, Wilson JR, Gamblin SJ. Justin N, et al. Nat Commun. 2016 Apr 28;7:11316. doi: 10.1038/ncomms11316. Nat Commun. 2016. PMID: 27121947 Free PMC article.

7

Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2.

Jiao L, Liu X. Jiao L, et al. Science. 2015 Oct 16;350(6258):aac4383. doi: 10.1126/science.aac4383. Epub 2015 Oct 15. Science. 2015. PMID: 26472914 Free PMC article.

8

Corepressor protein CDYL functions as a molecular bridge between polycomb repressor complex 2 and repressive chromatin mark trimethylated histone lysine 27.

Zhang Y, Yang X, Gui B, Xie G, Zhang D, Shang Y, Liang J. Zhang Y, et al. J Biol Chem. 2011 Dec 9;286(49):42414-42425. doi: 10.1074/jbc.M111.271064. Epub 2011 Oct 17. J Biol Chem. 2011. PMID: 22009739 Free PMC article.

9

Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms.

Margueron R, Li G, Sarma K, Blais A, Zavadil J, Woodcock CL, Dynlacht BD, Reinberg D. Margueron R, et al. Mol Cell. 2008 Nov 21;32(4):503-18. doi: 10.1016/j.molcel.2008.11.004. Mol Cell. 2008. PMID: 19026781 Free PMC article.

10

A neoplastic gene fusion mimics trans-splicing of RNAs in normal human cells.

Li H, Wang J, Mor G, Sklar J. Li H, et al. Science. 2008 Sep 5;321(5894):1357-61. doi: 10.1126/science.1156725. Science. 2008. PMID: 18772439

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