Abstract
From Alzheimer's visual cortex mRNA, a novel cDNA sequence with homology to the carboxy-terminal two-thirds of known serine proteinases was isolated (43% identity with human trypsinogen II). The corresponding mRNA has a size of approximately 8 kb and is expressed in low amounts in all human tissues tested.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alzheimer Disease / enzymology
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Amino Acid Sequence
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Base Sequence
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Brain / enzymology*
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Cloning, Molecular
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DNA, Complementary / chemistry
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DNA, Complementary / isolation & purification
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Humans
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Molecular Sequence Data
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RNA, Messenger / analysis
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Serine Endopeptidases / genetics*
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Visual Cortex / enzymology
Substances
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DNA, Complementary
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RNA, Messenger
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Serine Endopeptidases