A cDNA encoding the human type I hair keratin hHal

P Fink; M A Rogers; B Korge; H Winter; J Schweizer

doi:10.1016/0167-4781(95)00122-w

A cDNA encoding the human type I hair keratin hHal

Biochim Biophys Acta. 1995 Oct 17;1264(1):12-4. doi: 10.1016/0167-4781(95)00122-w.

Authors

P Fink¹, M A Rogers, B Korge, H Winter, J Schweizer

Affiliation

¹ German Cancer Research Center, Research Program 2 (Tumor Cell Regulation), Heidelberg, Germany.

PMID: 7578244
DOI: 10.1016/0167-4781(95)00122-w

Abstract

A full-length cDNA of a human type I hair keratin was isolated that encodes a protein of 416 amino acids. Northern blot analysis shows that the mRNA is present in human scalp but not in hairless skin. Based on sequence homology comparisons with the four known mouse type I hair keratins mHal-4 the keratin could be identified as the human hair keratin hHal.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Base Sequence
DNA, Complementary / genetics
DNA, Complementary / isolation & purification
Hair / chemistry*
Humans
Keratins / genetics*
Molecular Sequence Data
RNA, Messenger / analysis
Scalp / chemistry

Substances

DNA, Complementary
RNA, Messenger
Keratins

Associated data

GENBANK/X86570