Possible localization of Gc-System on chromosome 4. Loss of long arm 4 material associated with father-child incompatibility within the Gc-System

M Mikkelsen; P Jacobsen; K Henningsen

doi:10.1159/000152857

Possible localization of Gc-System on chromosome 4. Loss of long arm 4 material associated with father-child incompatibility within the Gc-System

Hum Hered. 1977;27(2):105-7. doi: 10.1159/000152857.

Authors

M Mikkelsen, P Jacobsen, K Henningsen

PMID: 558959
DOI: 10.1159/000152857

Abstract

A mentally retarded girl with a sporadically occurring B/F translocation was reexamined with new banding techniques. Chromosome material from the long arm of chromosome 4 was inserted into the long arm of chromosome 20. The segment 4q11 leads to q13 was lost. The formerly reported abnormal segregation of the Gc-system was verified. The localization of the Gc-locus on the lost segment cannot be ruled out.

MeSH terms

Blood Group Antigens*
Chromosome Aberrations*
Chromosomes, Human, 4-5*
Female
Humans
Intellectual Disability / genetics
Karyotyping
Male
Pedigree
Translocation, Genetic*

Substances

Blood Group Antigens