Assignment of the human antithrombin III structural gene to chromosome 1q23-25

Cytogenet Cell Genet. 1985;39(1):67-9. doi: 10.1159/000132105.

Abstract

The human antithrombin III (ATIII) structural gene was mapped by in situ hybridization and quantitative analysis of ATIII gene dosage in DNA isolated from carriers of chromosome 1 deletions. These studies indicate that the ATIII structural gene maps to human chromosome q23-q25 and so is likely identical to AT3.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antithrombin III / genetics*
  • Chromosome Banding
  • Chromosome Mapping
  • Chromosomes, Human, 1-3*
  • Genes
  • Humans
  • Nucleic Acid Hybridization

Substances

  • Antithrombin III