CPSF4 promotes triple negative breast cancer metastasis by upregulating MDM4

Signal Transduct Target Ther. 2021 May 19;6(1):184. doi: 10.1038/s41392-021-00565-9.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Cycle Proteins / biosynthesis*
  • Cell Cycle Proteins / genetics
  • Cell Proliferation*
  • Cleavage And Polyadenylation Specificity Factor / genetics
  • Cleavage And Polyadenylation Specificity Factor / metabolism*
  • Female
  • Gene Expression Regulation, Neoplastic*
  • Humans
  • Neoplasm Metastasis
  • Proto-Oncogene Proteins / biosynthesis*
  • Proto-Oncogene Proteins / genetics
  • Triple Negative Breast Neoplasms / genetics
  • Triple Negative Breast Neoplasms / metabolism*
  • Triple Negative Breast Neoplasms / pathology
  • Up-Regulation*

Substances

  • CPSF4 protein, human
  • Cell Cycle Proteins
  • Cleavage And Polyadenylation Specificity Factor
  • MDM4 protein, human
  • Proto-Oncogene Proteins