RAB27A/Melanophilin Blocker Inhibits Melanoma Cell Motility and Invasion

J Invest Dermatol. 2020 Jul;140(7):1470-1473.e3. doi: 10.1016/j.jid.2019.12.023. Epub 2020 Jan 22.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptor Proteins, Signal Transducing / metabolism*
  • Animals
  • Cell Movement
  • Humans
  • Immunotherapy
  • Lysosomes / metabolism
  • Melanocytes / metabolism
  • Melanoma / drug therapy
  • Melanoma / metabolism*
  • Melanoma, Experimental
  • Melanosomes / metabolism
  • Mice
  • Neoplasm Invasiveness
  • Prognosis
  • Skin Neoplasms / drug therapy
  • Skin Neoplasms / metabolism*
  • rab27 GTP-Binding Proteins / metabolism*

Substances

  • Adaptor Proteins, Signal Transducing
  • MLPH protein, human
  • Mlph protein, mouse
  • rab27 GTP-Binding Proteins
  • RAB27A protein, human
  • Rab27a protein, mouse