Deposition of mutant ubiquitin in parkinsonism-dementia complex of Guam

Acta Neuropathol Commun. 2017 Nov 9;5(1):82. doi: 10.1186/s40478-017-0490-0.

Bert M Verheijen^{1

2}, Tomoyo Hashimoto³, Kiyomitsu Oyanagi^{4

5}, Fred W van Leeuwen⁶

¹ Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands. l.m.verheijen-3@umcutrecht.nl.
² Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands. l.m.verheijen-3@umcutrecht.nl.
³ Department of Neurology, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan.
⁴ Division of Neuropathology, Department of Brain Disease Research, Shinshu University School of Medicine, Nagano, Japan.
⁵ Brain Research Laboratory, Hatsuishi Hospital, Chiba, Japan.
⁶ Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.

No abstract available

Keywords: Guam; Mutant ubiquitin; Parkinsonism-dementia complex; TDP-43; Ubiquitin-proteasome system.

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