Different Mutations of Gap Junction Connexin 47 Lead to Discrepant Activation of Unfolded Protein Response Pathway in Pelizaeus-Merzbacher-Like Disease

Neuropediatrics. 2017 Dec;48(6):426-431. doi: 10.1055/s-0037-1603978. Epub 2017 Jul 16.

Authors

Na Chen^{1

2}, Jingmin Wang¹, Yuwu Jiang¹, Ye Wu¹, Hongjun Hao³, Taoyun Ji¹

Affiliations

¹ Department of Pediatrics, Peking University First Hospital, Beijing, China.
² Department of Pediatrics, Capital Medical University, Beijing Tian Tan Hospital, Beijing, China.
³ Department of Neurology, Peking University First Hospital, Beijing, China.

PMID: 28712094
DOI: 10.1055/s-0037-1603978

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Apoptosis / physiology
Cell Line
Cell Survival / physiology
Connexins / genetics*
Connexins / metabolism
Humans
Mutation*
Oligodendroglia / metabolism
Pelizaeus-Merzbacher Disease / genetics*
Pelizaeus-Merzbacher Disease / metabolism
Protein Domains
Signal Transduction / genetics
Transfection
Unfolded Protein Response / genetics*
Unfolded Protein Response / physiology

Substances

Connexins
connexin 47