Case of Rectal GI Stromal Tumor Demonstrating that KIT and PDGFRA Mutations Are Not Always Mutually Exclusive

J Clin Oncol. 2016 Apr 20;34(12):e107-9. doi: 10.1200/JCO.2013.49.1258. Epub 2014 Jul 14.

Authors

Riccardo Ricci¹, Maurizio Martini², Tonia Cenci², Armando Antinori², Alessandra Cassano², Luigi M Larocca²

Affiliations

¹ Catholic University, Rome, Italy riccardoricci@rm.unicatt.it.
² Catholic University, Rome, Italy.

PMID: 25024074
DOI: 10.1200/JCO.2013.49.1258

No abstract available

Publication types

Case Reports

MeSH terms

Base Sequence
Biomarkers, Tumor / analysis
Biomarkers, Tumor / genetics*
Biopsy
DNA Mutational Analysis
Female
Gastrointestinal Stromal Tumors / chemistry
Gastrointestinal Stromal Tumors / genetics*
Gastrointestinal Stromal Tumors / pathology
Gastrointestinal Stromal Tumors / surgery
Genetic Predisposition to Disease
Humans
Immunohistochemistry
Middle Aged
Molecular Sequence Data
Mutation*
Phenotype
Proto-Oncogene Proteins c-kit / genetics*
Receptor, Platelet-Derived Growth Factor alpha / genetics*
Rectal Neoplasms / chemistry
Rectal Neoplasms / genetics*
Rectal Neoplasms / pathology
Rectal Neoplasms / surgery

Substances

Biomarkers, Tumor
Proto-Oncogene Proteins c-kit
Receptor, Platelet-Derived Growth Factor alpha