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Factor H-related protein 4 activates complement by serving as a platform for the assembly of alternative pathway C3 convertase via its interaction with C3b protein.
J Biol Chem. 2012 Jun 1;287(23):19528-36. doi: 10.1074/jbc.M112.364471. Epub 2012 Apr 19.
J Biol Chem. 2012.
PMID: 22518841
Free PMC article.
Myeloperoxidase directs properdin-mediated complement activation.
O'Flynn J, Dixon KO, Faber Krol MC, Daha MR, van Kooten C.
O'Flynn J, et al.
J Innate Immun. 2014;6(4):417-25. doi: 10.1159/000356980. Epub 2013 Dec 20.
J Innate Immun. 2014.
PMID: 24355864
Free PMC article.
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Monomeric C-reactive protein inhibits renal cell-directed complement activation mediated by properdin.
O'Flynn J, van der Pol P, Dixon KO, Prohászka Z, Daha MR, van Kooten C.
O'Flynn J, et al.
Am J Physiol Renal Physiol. 2016 Jun 1;310(11):F1308-16. doi: 10.1152/ajprenal.00645.2014. Epub 2016 Mar 16.
Am J Physiol Renal Physiol. 2016.
PMID: 26984957
Free article.
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Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator.
Micklisch S, Lin Y, Jacob S, Karlstetter M, Dannhausen K, Dasari P, von der Heide M, Dahse HM, Schmölz L, Grassmann F, Alene M, Fauser S, Neumann H, Lorkowski S, Pauly D, Weber BH, Joussen AM, Langmann T, Zipfel PF, Skerka C.
Micklisch S, et al.
J Neuroinflammation. 2017 Jan 5;14(1):4. doi: 10.1186/s12974-016-0776-3.
J Neuroinflammation. 2017.
PMID: 28086806
Free PMC article.
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Complement factor P is a ligand for the natural killer cell-activating receptor NKp46.
Narni-Mancinelli E, Gauthier L, Baratin M, Guia S, Fenis A, Deghmane AE, Rossi B, Fourquet P, Escalière B, Kerdiles YM, Ugolini S, Taha MK, Vivier E.
Narni-Mancinelli E, et al.
Sci Immunol. 2017 Apr 28;2(10):eaam9628. doi: 10.1126/sciimmunol.aam9628.
Sci Immunol. 2017.
PMID: 28480349
Free PMC article.
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FHR-1 Binds to C-Reactive Protein and Enhances Rather than Inhibits Complement Activation.
Csincsi ÁI, Szabó Z, Bánlaki Z, Uzonyi B, Cserhalmi M, Kárpáti É, Tortajada A, Caesar JJE, Prohászka Z, Jokiranta TS, Lea SM, Rodríguez de Córdoba S, Józsi M.
Csincsi ÁI, et al.
J Immunol. 2017 Jul 1;199(1):292-303. doi: 10.4049/jimmunol.1600483. Epub 2017 May 22.
J Immunol. 2017.
PMID: 28533443
Free article.
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A reference map of the human binary protein interactome.
Luck K, Kim DK, Lambourne L, Spirohn K, Begg BE, Bian W, Brignall R, Cafarelli T, Campos-Laborie FJ, Charloteaux B, Choi D, Coté AG, Daley M, Deimling S, Desbuleux A, Dricot A, Gebbia M, Hardy MF, Kishore N, Knapp JJ, Kovács IA, Lemmens I, Mee MW, Mellor JC, Pollis C, Pons C, Richardson AD, Schlabach S, Teeking B, Yadav A, Babor M, Balcha D, Basha O, Bowman-Colin C, Chin SF, Choi SG, Colabella C, Coppin G, D'Amata C, De Ridder D, De Rouck S, Duran-Frigola M, Ennajdaoui H, Goebels F, Goehring L, Gopal A, Haddad G, Hatchi E, Helmy M, Jacob Y, Kassa Y, Landini S, Li R, van Lieshout N, MacWilliams A, Markey D, Paulson JN, Rangarajan S, Rasla J, Rayhan A, Rolland T, San-Miguel A, Shen Y, Sheykhkarimli D, Sheynkman GM, Simonovsky E, Taşan M, Tejeda A, Tropepe V, Twizere JC, Wang Y, Weatheritt RJ, Weile J, Xia Y, Yang X, Yeger-Lotem E, Zhong Q, Aloy P, Bader GD, De Las Rivas J, Gaudet S, Hao T, Rak J, Tavernier J, Hill DE, Vidal M, Roth FP, Calderwood MA.
Luck K, et al.
Nature. 2020 Apr;580(7803):402-408. doi: 10.1038/s41586-020-2188-x. Epub 2020 Apr 8.
Nature. 2020.
PMID: 32296183
Free PMC article.
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