Dll1/Notch activation accelerates multiple myeloma disease development by promoting CD138+ MM-cell proliferation

Leukemia. 2012 Jun;26(6):1402-5. doi: 10.1038/leu.2011.332. Epub 2011 Nov 18.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blotting, Western
  • Calcium-Binding Proteins
  • Cell Differentiation
  • Cell Proliferation*
  • Humans
  • Intercellular Signaling Peptides and Proteins / genetics
  • Intercellular Signaling Peptides and Proteins / metabolism*
  • Membrane Proteins / genetics
  • Membrane Proteins / metabolism*
  • Mice
  • Multiple Myeloma / genetics
  • Multiple Myeloma / metabolism*
  • Multiple Myeloma / pathology*
  • RNA, Messenger / genetics
  • Real-Time Polymerase Chain Reaction
  • Receptors, Notch / genetics
  • Receptors, Notch / metabolism*
  • Syndecan-1 / genetics
  • Syndecan-1 / metabolism*
  • Tumor Cells, Cultured

Substances

  • Calcium-Binding Proteins
  • DLK1 protein, human
  • Intercellular Signaling Peptides and Proteins
  • Membrane Proteins
  • RNA, Messenger
  • Receptors, Notch
  • SDC1 protein, human
  • Syndecan-1