Aim: By genechip cDNA microarray, the genes expressions of Stearoyl-coenzyme A desaturase (Scd-2) and brain fatty acid-binding protein (B-FABP) were studied in the central nervous system (CNS) of the mice to discuss the mechanism of exercise-induced fatigue.
Methods: Building the model of fatigued animal and using the genechip cDNA microarray, the genes expressions were analyzed between the control group and fatigue group mice.
Results: The genes expression of Scd-2 and B-FABP were obvious different in the brain of fatigued group mice than of control group.
Conclusion: Exercise-induced nerve center fatigue is correlated with genes expressions of lipid metabolism.