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The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome.
Genes Dev. 2010 Jul 1;24(13):1434-47. doi: 10.1101/gad.1925010.
Genes Dev. 2010.
PMID: 20595234
Free PMC article.
PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.
Maréchal A, Li JM, Ji XY, Wu CS, Yazinski SA, Nguyen HD, Liu S, Jiménez AE, Jin J, Zou L.
Maréchal A, et al.
Mol Cell. 2014 Jan 23;53(2):235-246. doi: 10.1016/j.molcel.2013.11.002. Epub 2013 Dec 12.
Mol Cell. 2014.
PMID: 24332808
Free PMC article.
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