Serum antimullerian hormone (AMH) levels are elevated in adolescent girls with polycystic ovaries and the polycystic ovarian syndrome (PCOS)

Fertil Steril. 2010 Aug;94(3):1118-21. doi: 10.1016/j.fertnstert.2009.11.002. Epub 2010 Jan 8.

Abstract

Polycystic ovarian syndrome (PCOS) is a common endocrine disorder in adolescents, with potentially significant lifelong consequences. This prospective study set out to determine if the investigators could derive a threshold value of antimullerian hormone (AMH) that would predict its presence according to two internationally recognized definitions using a simple measurement, avoiding more extensive and potentially more invasive investigations. The study failed to demonstrate, in a general adolescent population, that serum AMH is a reliable predictor of PCO morphology or for the presence of PCOS.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Anti-Mullerian Hormone / blood*
  • Biomarkers / blood
  • Body Mass Index
  • Cohort Studies
  • Diagnostic Techniques, Endocrine
  • Female
  • Humans
  • Organ Size
  • Ovarian Cysts / blood*
  • Ovarian Cysts / diagnosis
  • Ovarian Cysts / pathology
  • Ovary / pathology
  • Polycystic Ovary Syndrome / blood*
  • Polycystic Ovary Syndrome / diagnosis
  • Polycystic Ovary Syndrome / pathology
  • Sensitivity and Specificity
  • Up-Regulation

Substances

  • Biomarkers
  • Anti-Mullerian Hormone