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Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling.
J Biol Chem. 2008 Apr 4;283(14):9359-68. doi: 10.1074/jbc.M707108200. Epub 2008 Jan 30.
J Biol Chem. 2008.
PMID: 18234671
Free PMC article.
A novel Wnt5a-Frizzled4 signaling pathway mediates activity-independent dendrite morphogenesis via the distal PDZ motif of Frizzled 4.
Bian WJ, Miao WY, He SJ, Wan ZF, Luo ZG, Yu X.
Bian WJ, et al.
Dev Neurobiol. 2015 Aug;75(8):805-22. doi: 10.1002/dneu.22250. Epub 2014 Dec 1.
Dev Neurobiol. 2015.
PMID: 25424568
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