Chromosomal location of the human tumor necrosis factor receptor genes

E Baker; L Z Chen; C A Smith; D F Callen; R Goodwin; G R Sutherland

doi:10.1159/000133127

Chromosomal location of the human tumor necrosis factor receptor genes

Cytogenet Cell Genet. 1991;57(2-3):117-8. doi: 10.1159/000133127.

Authors

E Baker¹, L Z Chen, C A Smith, D F Callen, R Goodwin, G R Sutherland

Affiliation

¹ Department of Cytogenetics and Molecular Genetics, Adelaide Children's Hospital, North Adelaide, Australia.

PMID: 1655358
DOI: 10.1159/000133127

Abstract

TNFR1 and TNFR2, the genes encoding the two forms of the human tumor necrosis factor receptor, were localized to normal human chromosomes by in situ hybridization and Southern blot analysis of a series of human x mouse hybrid cell lines. TNFR1 maps to 12p13 and TNFR2 maps to 1p36.

MeSH terms

Blotting, Southern
Chromosome Banding
Chromosome Mapping
Chromosomes, Human, Pair 1*
Chromosomes, Human, Pair 12*
Humans
Hybrid Cells / physiology
Nucleic Acid Hybridization
Receptors, Cell Surface / genetics*
Receptors, Tumor Necrosis Factor
Restriction Mapping
Tumor Necrosis Factor-alpha / physiology

Substances

Receptors, Cell Surface
Receptors, Tumor Necrosis Factor
Tumor Necrosis Factor-alpha