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Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase.
Mol Cell. 2005 Sep 16;19(6):829-40. doi: 10.1016/j.molcel.2005.08.009.
Mol Cell. 2005.
PMID: 16168377
Free article.
Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78.
Lee JN, Song B, DeBose-Boyd RA, Ye J.
Lee JN, et al.
J Biol Chem. 2006 Dec 22;281(51):39308-15. doi: 10.1074/jbc.M608999200. Epub 2006 Oct 16.
J Biol Chem. 2006.
PMID: 17043353
Free article.
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