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Intracellular serpin SERPINB6 (PI6) is abundantly expressed by human mast cells and forms complexes with beta-tryptase monomers.
Blood. 2004 Apr 1;103(7):2710-7. doi: 10.1182/blood-2003-08-2981. Epub 2003 Dec 11.
Blood. 2004.
PMID: 14670919
Free article.
SerpinB6 is an inhibitor of kallikrein-8 in keratinocytes.
Scott FL, Sun J, Whisstock JC, Kato K, Bird PI.
Scott FL, et al.
J Biochem. 2007 Oct;142(4):435-42. doi: 10.1093/jb/mvm156. Epub 2007 Aug 30.
J Biochem. 2007.
PMID: 17761692
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A truncating mutation in SERPINB6 is associated with autosomal-recessive nonsyndromic sensorineural hearing loss.
Sirmaci A, Erbek S, Price J, Huang M, Duman D, Cengiz FB, Bademci G, Tokgöz-Yilmaz S, Hişmi B, Ozdağ H, Oztürk B, Kulaksizoğlu S, Yildirim E, Kokotas H, Grigoriadou M, Petersen MB, Shahin H, Kanaan M, King MC, Chen ZY, Blanton SH, Liu XZ, Zuchner S, Akar N, Tekin M.
Sirmaci A, et al.
Am J Hum Genet. 2010 May 14;86(5):797-804. doi: 10.1016/j.ajhg.2010.04.004. Epub 2010 May 6.
Am J Hum Genet. 2010.
PMID: 20451170
Free PMC article.
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