Abstract
We have characterized a novel human gene, FSD1, on chromosome 19. FSD1 has a BBC, FN3 and SPRY domain, it is distantly related to the midline 1 gene and is expressed only in the brain. We have established its exon-intron structure and we have identified the corresponding orthologous genes in other species. In addition, the identification of FSD1 has led us to identify a homologous counterpart sequence on chromosome 9.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alternative Splicing
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Amino Acid Sequence
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Animals
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Base Sequence
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Brain / metabolism
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Brain / pathology
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Chromosomes, Human, Pair 19*
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DNA, Complementary
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Exons
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Fibronectins / genetics
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Gene Expression Profiling
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Humans
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Introns
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Mice
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Molecular Sequence Data
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Nerve Tissue Proteins / genetics*
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Nerve Tissue Proteins / metabolism
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Proteins / genetics*
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Proteins / metabolism
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Sequence Homology, Amino Acid
Substances
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DNA, Complementary
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FSD1 protein, human
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Fibronectins
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Fsd1 protein, mouse
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Nerve Tissue Proteins
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Proteins
Associated data
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GENBANK/AF316829
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GENBANK/AF316830