Characterization of human FSD1, a novel brain specific gene on chromosome 19 with paralogy to 9q31

Biochim Biophys Acta. 2001 Mar 19;1518(1-2):200-3. doi: 10.1016/s0167-4781(01)00178-6.

Abstract

We have characterized a novel human gene, FSD1, on chromosome 19. FSD1 has a BBC, FN3 and SPRY domain, it is distantly related to the midline 1 gene and is expressed only in the brain. We have established its exon-intron structure and we have identified the corresponding orthologous genes in other species. In addition, the identification of FSD1 has led us to identify a homologous counterpart sequence on chromosome 9.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alternative Splicing
  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Brain / metabolism
  • Brain / pathology
  • Chromosomes, Human, Pair 19*
  • DNA, Complementary
  • Exons
  • Fibronectins / genetics
  • Gene Expression Profiling
  • Humans
  • Introns
  • Mice
  • Molecular Sequence Data
  • Nerve Tissue Proteins / genetics*
  • Nerve Tissue Proteins / metabolism
  • Proteins / genetics*
  • Proteins / metabolism
  • Sequence Homology, Amino Acid

Substances

  • DNA, Complementary
  • FSD1 protein, human
  • Fibronectins
  • Fsd1 protein, mouse
  • Nerve Tissue Proteins
  • Proteins

Associated data

  • GENBANK/AF316829
  • GENBANK/AF316830