Isolation and characterisation of a cDNA encoding the precursor for a novel member of the acyl-CoA dehydrogenase gene family

Biochim Biophys Acta. 1999 Sep 3;1446(3):371-6. doi: 10.1016/s0167-4781(99)00102-5.

Abstract

A gene encoding the precursor for a novel member of the human acyl-CoA dehydrogenase (ACD) gene family has been isolated which maps to human chromosome 11q25. The cDNA contains an open reading frame of 1248 nucleotides encoding a predicted 415-amino-acid peptide, and shares considerable sequence similarity with other members of the ACD family.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acyl-CoA Dehydrogenase
  • Acyl-CoA Dehydrogenases / chemistry
  • Acyl-CoA Dehydrogenases / genetics*
  • Amino Acid Sequence
  • Base Sequence
  • Brain / metabolism
  • Chromosomes, Human, Pair 11
  • DNA, Complementary / chemistry
  • DNA, Complementary / isolation & purification
  • Humans
  • Molecular Sequence Data
  • Protein Precursors / chemistry
  • Protein Precursors / genetics*
  • RNA, Messenger / analysis
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sequence Alignment
  • Skin / metabolism

Substances

  • DNA, Complementary
  • Protein Precursors
  • RNA, Messenger
  • Acyl-CoA Dehydrogenases
  • ACAD8 protein, human
  • Acyl-CoA Dehydrogenase

Associated data

  • GENBANK/AF126245