RecName: Full=RecQ-like DNA helicase BLM; AltName: Full=Bloom syndrome - Protein

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BLM helicase protein negatively regulates stress granule formation through unwinding RNA G-quadruplex structures. [Nucleic Acids Res. 2023]
BLM helicase protein negatively regulates stress granule formation through unwinding RNA G-quadruplex structures.
Danino YM, Molitor L, Rosenbaum-Cohen T, Kaiser S, Cohen Y, Porat Z, Marmor-Kollet H, Katina C, Savidor A, Rotkopf R, et al. Nucleic Acids Res. 2023 Sep 22; 51(17):9369-9384.
Downregulation of BLM RecQ helicase inhibits proliferation, promotes the apoptosis and enhances the sensitivity of bladder cancer cells to cisplatin. [Mol Med Rep. 2022]
Downregulation of BLM RecQ helicase inhibits proliferation, promotes the apoptosis and enhances the sensitivity of bladder cancer cells to cisplatin.
Feng S, Qian X, Feng D, Zhang X. Mol Med Rep. 2022 Oct; 26(4). Epub 2022 Aug 25.
Bloom Syndrome Helicase Compresses Single-Stranded DNA into Phase-Separated Condensates. [Angew Chem Int Ed Engl. 2022]
Bloom Syndrome Helicase Compresses Single-Stranded DNA into Phase-Separated Condensates.
Wang T, Hu J, Li Y, Bi L, Guo L, Jia X, Zhang X, Li D, Hou XM, Modesti M, et al. Angew Chem Int Ed Engl. 2022 Sep 26; 61(39):e202209463. Epub 2022 Aug 23.

RefSeq genomic sequence
See the genomic reference sequence for the BLM gene (NG_007272.1).
RefSeq protein isoforms
See 10 reference sequence protein isoforms for the BLM gene.

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P54132 [Domain Mapping of Disease Mut...]
P54132
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=RecQ-like DNA helicase BLM; AltName: Full=Bloom syndrome protein; ...
RecName: Full=RecQ-like DNA helicase BLM; AltName: Full=Bloom syndrome protein; AltName: Full=DNA 3'-5' helicase BLM; AltName: Full=DNA helicase, RecQ-like type 2; Short=RecQ2; AltName: Full=RecQ protein-like 3
gi|1705486|sp|P54132.1|BLM_HUMAN

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