serine/threonine-protein kinase 40 isoform 2 [Homo sapiens]

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Protein 3D Structure

Serine/threonine-protein kinase 40 (STK40) kinase homology domain

PDB: 5L2Q

Source: Homo sapiens

Method: X-ray Diffraction

Resolution: 2.53 Å

Articles about the STK40 gene

Construction and validation of a novel senescence-related risk score can help predict the prognosis and tumor microenvironment of gastric cancer patients and determine that STK40 can affect the ROS accumulation and proliferation ability of gastric cancer cells. [Front Immunol. 2023]
Construction and validation of a novel senescence-related risk score can help predict the prognosis and tumor microenvironment of gastric cancer patients and determine that STK40 can affect the ROS accumulation and proliferation ability of gastric cancer cells.
Sun W, Yuan Y, Chen J, Bao Q, Shang M, Sun P, Peng H. Front Immunol. 2023; 14:1259231. Epub 2023 Oct 17.
Identification of biomarkers of human skin ageing in both genders. Wnt signalling - a label of skin ageing? [PLoS One. 2012]
Identification of biomarkers of human skin ageing in both genders. Wnt signalling - a label of skin ageing?
Makrantonaki E, Brink TC, Zampeli V, Elewa RM, Mlody B, Hossini AM, Hermes B, Krause U, Knolle J, Abdallah M, et al. PLoS One. 2012; 7(11):e50393. Epub 2012 Nov 30.
MicroRNA-31 is overexpressed in psoriasis and modulates inflammatory cytokine and chemokine production in keratinocytes via targeting serine/threonine kinase 40. [J Immunol. 2013]
MicroRNA-31 is overexpressed in psoriasis and modulates inflammatory cytokine and chemokine production in keratinocytes via targeting serine/threonine kinase 40.
Xu N, Meisgen F, Butler LM, Han G, Wang XJ, Söderberg-Nauclér C, Ståhle M, Pivarcsi A, Sonkoly E. J Immunol. 2013 Jan 15; 190(2):678-88. Epub 2012 Dec 10.

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Reference sequence information

RefSeq mRNA
See reference mRNA sequence for the STK40 gene (NM_001282547.2).
RefSeq protein isoforms
See 3 reference sequence protein isoforms for the STK40 gene.

More about the STK40 gene

Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Predicted to be invo...
Also Known As: SHIK, SgK495

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NP_001269476 [Domain Mapping of Disease Mut...]
NP_001269476
Domain Mapping of Disease Mutations
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OncoMX cancer biomarker resource
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Articles about the STK40 gene

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