RecName: Full=Neuronal pentraxin-2; Short=NP2; AltName: Full=Neuronal - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

A model of human neural networks reveals NPTX2 pathology in ALS and FTLD. [Nature. 2024]
A model of human neural networks reveals NPTX2 pathology in ALS and FTLD.
Hruska-Plochan M, Wiersma VI, Betz KM, Mallona I, Ronchi S, Maniecka Z, Hock EM, Tantardini E, Laferriere F, Sahadevan S, et al. Nature. 2024 Feb; 626(8001):1073-1083. Epub 2024 Feb 14.
Assessments of the Utilities of CSF NPTX2 for Disease Progression in Cognitively Normal Individuals Who Progress to Clinical MCI and AD. [Ann Neurol. 2023]
Assessments of the Utilities of CSF NPTX2 for Disease Progression in Cognitively Normal Individuals Who Progress to Clinical MCI and AD.
Shaw LM, Galasko D. Ann Neurol. 2023 Oct; 94(4):618-619.
NPTX2 in Cerebrospinal Fluid Predicts the Progression From Normal Cognition to Mild Cognitive Impairment. [Ann Neurol. 2023]
NPTX2 in Cerebrospinal Fluid Predicts the Progression From Normal Cognition to Mild Cognitive Impairment.
Soldan A, Oh S, Ryu T, Pettigrew C, Zhu Y, Moghekar A, Xiao MF, Pontone GM, Albert M, Na CH, et al. Ann Neurol. 2023 Oct; 94(4):620-631. Epub 2023 Jul 25.

RefSeq genomic sequence
See the genomic reference sequence for the NPTX2 gene (NG_009905.1).
RefSeq protein
See the reference protein sequence for neuronal pentraxin-2 precursor (NP_002514.1).

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures
Related Structures (Summary)
Related structures

P47972 [Domain Mapping of Disease Mut...]
P47972
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Neuronal pentraxin-2; Short=NP2; AltName: Full=Neuronal pentraxin ...
RecName: Full=Neuronal pentraxin-2; Short=NP2; AltName: Full=Neuronal pentraxin II; Short=NP-II; Flags: Precursor
gi|20981708|sp|P47972.2|NPTX2_HUMAN

Protein
PTPN5 protein tyrosine phosphatase non-receptor type 5 [Homo sapiens]
PTPN5 protein tyrosine phosphatase non-receptor type 5 [Homo sapiens]
Gene ID:84867

Gene
Homo sapiens collagen type IX alpha 2 chain (COL9A2), mRNA
Homo sapiens collagen type IX alpha 2 chain (COL9A2), mRNA
gi|1523761391|ref|NM_001852.4|

Nucleotide
RefSeq Protein Links for Gene (Select 23594) (3)
Protein
Homo sapiens isolate:CHM13
Homo sapiens isolate:CHM13
Homo sapiens isolate:CHM13 RefSeq Genome sequencing and assembly

BioProject

Your browsing activity is empty.

Activity recording is turned off.

Protein